摘要
目的用受试者工作特征曲线(ROC)分析法评价超声与钼靶摄影术在乳腺癌筛查和早期诊断中的价值。方法采用X线钼靶、超声和二者联合的3种检测方法对66例乳腺肿块患者的影像资料进行观察,并根据乳腺病灶的大小、形态、边缘、包膜、内部回声、后方回声以及有无微钙化灶等特征,做出影像学的诊断,以手术病理诊断为金标准。按完全肯定良性、可能良性、不确定、可能恶性、肯定恶性5个诊断精度,分别作出3种影像方法诊断的乳腺肿块良恶性的ROC分析评价。结果ROC评价显示钼靶和超声联合应用的ROC曲线比其他两条曲线更偏左上角,其曲线下面积为两者联合(0.967)>超声(0.886)>钼靶(0.856)。两者联合运用对乳腺肿块良恶性诊断较钼靶或超声单独运用准确(P<0.05),且钼靶与超声检查间无明显差异(P>0.05)。结论超声和钼靶摄影术在乳腺癌筛查和早期诊断中有一定的价值,两者联合运用优于单独检查。
Objective To evaluate the diagnostic value of ultrasound and mammography in the screening and early diagnosis of breast carcinoma using receiver operating characteristic （ROC） analysis. Methods Sixty-six patients with clinically suspected breast carcinoma were respectively examined with ultrasound, mammography and combination of ultrasound and mammography. The diagnosis was made according to size, shape, borderline, envelope, inner and post echo, microcalcification, ect. The surgical findings and pathology were taken as ＂gold standard＂, the results were evaluated by ROC analysis using five-point categorical scale ranged from deftnitely abnormal to definitely norm. Results It was shown that the ROC curve for diagnosis with combination of ultrasound and mammography was closer to the ideal discrimination function than those with uhrasound or mammogrphy alone. The area under ROC curve for diagnosis with combination of ultrasound and mammography （0.967） was significantly （P 〈 0.05） larger than that with ultrasound （0.886） or mammography （0. 856）. Condusion Combination of uhrasound and mammographyalone can provide more value than ultrasound or mammography alone in the screening and early diagnosis of breast carcinoma .
出处
《临床超声医学杂志》
2008年第3期169-171,174,共4页
Journal of Clinical Ultrasound in Medicine
