摘要
目的:探讨小儿毒鼠药中毒致人体各重要器官损害的病理形态学改变。方法:通过6例临床胃液分析检出氟乙酰胺、毒鼠强中毒死亡病例,常规尸检取出内脏器官检查,经常规石蜡切片,HE染色,光镜检查。结果:6例中的中枢神经系统、肝脏、肾脏、心脏、消化道、肺脏、脾脏、肾上腺及骨髓等均见明显的病理改变。结论:毒鼠药氟乙酰胺、毒鼠强具有中毒量小、毒性大、病变严重的特点,导致多内脏器官功能衰竭而死亡。
Objective:To study the pathological changes of critical organs in children poisoned by rodenticides. Methods: 6 cases of autopsy were confirmed to be fluoroacetamide or tetramine poisoning by analysis of gastric fluid. The internal viscera were extracted, paraffin-embedded and observed by microscopic examination. Results:Significant pathological changes observed in 6 cases involved central nervous system, liver, kidney, heart, gastrointestinal tract, lung, spleen, adrenal gland and bone marrow. Conclusion: Fluoroacetamide and tetramine are highly toxic and pathogenic agents which may cause multiple organ failure and even death.
出处
《广州医学院学报》
2007年第4期34-36,共3页
Academic Journal of Guangzhou Medical College
关键词
毒鼠药中毒
氟乙酰胺
毒鼠强
小儿
尸检
ratsbane poisoning
fluoroacetamide
tetramine
children
autopsy