摘要
目的:分析社区感染铜绿假单胞菌对15种抗生素的耐药情况,为指导临床合理用药提供依据。方法:收集2005-2007年广州市荔湾区社区门诊患者的痰液及相关标本,按常规方法培养分离后,用VITEK-32全自动微生物分析仪鉴定,用K-B法作药物敏感试验,并进行统计分析。结果:148株铜绿假单胞菌敏感性最高的抗菌药物是亚胺培南(89.9%),其次分别为阿米卡星(70.3%)、哌拉西林(60.8%)、环丙沙星(58.8%)、庆大霉素(54.7%)。结论:铜绿假单胞菌耐药性日趋严重,治疗中应根据菌株耐药特点合理选择用药方案,以减少耐药菌株的加重与扩散。
Objective： To analysis the drug resistance of community-acquired infection with Pseudomonas aeruginosa（PA） to 15 types of antibiotics, and to provide evidences for clinical therapy. Methods： Sputum samples and other relevant specimens collected from clinic patients in Liwan communities between 2005 and 2007 ,were isolated for PA using routinal approach. The PA isolates were identified by VITEK-32 analyser, then subjected to antibiotic susceptibility test by K-B method. Results：：All the PA isolates （148 strains） were most susceptible to imipenem （89.9%） , followed by amikacin （ 70. 3% ） , piperacillin （ 60. 8% ）, ciprofloxacin （ 58. 8% ） and gentamycin （54. 7% ）. Conclusions： With the increasing challenge posed by drug-resistant PA, proper use of antibiotics should be practised according to drug susceptibility test, in order to avert worsening and widespreading of the resistant strains.
出处
《广州医学院学报》
2007年第4期40-42,共3页
Academic Journal of Guangzhou Medical College
基金
广东省医学科研基金(2007550)
广州市医药卫生科技项目(2007-YB-183)
广州市荔湾区科技计划项目(2007120848-3)
关键词
铜绿假单胞菌
社区感染
耐药性
Pseudomonas aeruginosa
community-aquired infection
drug resistance
