摘要
阻塞性睡眠呼吸暂停综合征（OSAS）是一全身多系统性疾病，其病因复杂，很大程度上受遗传因素的影响，且发病率有逐年上升趋势。其发病的主要危险因素包括肥胖、男性、中年和气道狭窄等。新近的研究多集中在心血管疾病和炎症因子与OSAS的关系以及相关基因位点多态性方面。
Obstructive sleep apnea syndrome （OSAS） is a multisystemic complex disease strongly influenced by genetic factors and its prevalence appears to be increasing. The main risk factors for OSAS are obesity,male gender,middle age,and the presence of a narrow airway. Recent researches pay more attention to cardiovascular diseases as well as related factors, inflammatory cytokines and related gene locus polymorphism.
出处
《国际呼吸杂志》
2008年第6期353-356,共4页
International Journal of Respiration
关键词
阻塞性睡眠呼吸暂停综合征
遗传易感性
肥胖
性别差异
炎症因子
Obstructive sleep apnea syndrome
Genetic susceptibility
Obesity
Sex difference
Inflammatory cytokine
