摘要
目的:筛选聚维酮碘泡腾片的处方。方法:将枸橼酸、碳酸氢钠、聚乙二醇4000按一定比例混合,作为片剂基本处方,以片剂的外观、崩解时限及发泡量为指标进行处方筛选。结果:所筛选处方压制的片剂外观光洁,在10min内完全崩解。结论:该片剂的质量主要与辅料的用量有关。
Objective：To optimize the formulation of iodine tablets. Methods：The formulations of the tablets were composed of a certain proportion of citromalic acid, NaHCO3 and polyglycol 4000 （PEG4000）. And the formulations were evaluated by the appearance, dissolution and effervescence. Results：The tablets prepared were fine in appearance and disintegrated within 10 min. Conclusion ：The quality of the tablets was mostly related to the amount of supplementary material.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2008年第5期400-401,404,共3页
Chinese Journal of New Drugs
基金
中国人民解放军海军医学研究所基金资助(07K301)
关键词
聚维酮碘
片剂
制备
电位滴定法
povidone iodine
tablet
preparation
electrolytic titration
