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药物联合治疗急性冠脉综合征40例临床护理 被引量:5

Clinical nursing care of 40 cases of acute coronary syndrome treated with combined medication
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摘要 目的:探讨药物氯吡格雷、阿托伐他汀、低分子肝素联合治疗急性冠脉综合征的效果及护理方法。方法:将80例急性冠脉综合征患者随机分为治疗组和对照组各40例,对照组给予常规治疗,治疗组在常规治疗基础上加服氯吡格雷、阿托伐他汀,同时皮下注射低分子肝素,两组均给予心理、饮食护理及健康教育。评估两组治疗后临床症状及心电图改善程度,监测活化部分凝血活酶时间(APTT)。结果:治疗组临床症状改善总有效率达95%,心电图改善总有效率达95%,对照组分别为80%和75%,两组比较有显著性差异(P<0.05,P<0.01)。结论:在常规治疗基础上联合使用药物氯吡格雷、阿托伐他汀、低分子肝素,可显著提高急性冠脉综合征治愈率。 Objective : To explore the effectiveness of combined medication with clopidogrel, atovastatin and low molecular weight heparins and nursing methods in the treatment of acute coronary syndrome. Methods : Eighty patients with acute coronary syndrome were randomly divided into control group (n = 40) and treatment group (n = 40 ). Patients were given routine treatment in control group, and clopidogrel, atovastatin and low molecular weight heparins were additionally given to patients besides routine treatment in treatment group. Nursing care in mentality, diet and health education were applied to both groups. Evaluation was made on clinical symptoms, improvement in ECG and APTT after treatment in the two groups. Results : The total effective rates of improvement were 95% in clinical symptoms and 95% in ECG in treatment group; 80% and 75% in control group. The significant difference was found in the comparison between the two groups ( P 〈0. 05, P 〈 0. 01 ). Conclusion: Combined medication with clopidogrel, atovastatin and low molecular weight heparins can obviously increase curative rate in the treatment of acute coronary syndrome.
作者 李英 王桂芳
机构地区 烟台毓璜顶医院
出处 《齐鲁护理杂志》 2008年第1期15-16,共2页 Journal of Qilu Nursing
关键词 急性冠脉综合征 氯吡格雷 阿托伐他汀 低分子肝素 Acute coronary syndrome Clopidogrel Atovastatin Low molecular weight heparins
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  • 1Braunwald E, Antman EM, Beasley JW, et al. ACC/AHA guidelines for the management of patients with unstable angina and non- ST- segment elevation myocardial infarction : a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Committee on the Management of Patients With Unstable Angina[J]. J Am Coll Cardiol, 2002,40(7) :1366 -1374.
  • 2许俊堂,胡大一主编.心血管溶栓的溶剂和抗栓疗法[M].北京:人民卫生出版社,189-190.
  • 3胡大一 马长生.心脏病学实践[M].北京:人民卫生出版社,2004.625-626.

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