摘要
利用透射电镜观察了正常成年鸡脾内红细胞的凋亡现象。结果显示，鸡脾内凋亡红细胞核染色质先呈现网眼样变化，后浓缩、边聚。凋亡红细胞整个被巨噬细胞吞噬，在其中分解变小成为凋亡小体。凋亡小体电子密度有的升高，有的降低，最后均被巨噬细胞消化清除。结果表明，有核的红细胞发生细胞凋亡，并借助于巨噬细胞的膜系统完成凋亡过程。
The apoptosis of fowl erythrocytes was observed by transmission electron microscopy. The results showed that the erythrocytes in spleen of chickens underwent apoptosis. The chromatin of the apoptotic erythrocytes displayed mesh-like changes, then they condensed and marginated. The apoptotic erythrocytes were wholly phagocytosed by the macrophages rapidly. In the macrophages, the apoptotic erythrocytes broke up into small apoptotic bodies. The electron density of some apoptotic bodies increased and they formed dense bodies. Meanwhile,that of the others decreased and they changed into transparent bodies. Finally,all the apoptotic bodies were eliminated by the macrophages. The results indicated that,the nucleated erythrocytes conducted apoptosis,and completed their apoptotic process with the aid of the membranous system of macrophages.
出处
《第一军医大学学报》
CSCD
1997年第3期209-211,共3页
Journal of First Military Medical University
关键词
红细胞
鸡
超微结构
细胞凋亡
apoptosis
erythrocytes
bird
ultrastructure
