摘要
目的:探讨文拉法辛的抗抑郁疗效及安全性。方法:采用随机对照方法,两组分别给予文拉法辛和阿米替林,采用HAMD,HAMA,TESS评定疗效及不良反应。结果:文拉法辛组显效率为87%,阿米替林组为81%,两组间比较无显著性差异(P>0.05),但文拉法辛起效较快,且不良反应少。结论:文拉法辛疗效肯定,不良反应少,安全性高。
Objective： To explore the clinical effect and safety of Venlafaxine in the treatment of the depression disorder. Methods：The patients were divided into two groups randomly and took Venlafaxine or Amitriptyline. Rating them by HAMD, HAMA and TESS scale. Results： 87% patients in Venlafaxine group and 81% in Amitriptyline group had obtained clinical effect. There was no significant deference between two groups （ P 〈 0.05 ）. But it was faster to work and had fewer side effects in Venlafaxine group than that in Amitriptyline group. Conclusions： Venlafaxine has affirmative clinical effect, little side effect and high safety in treating depres- sion disorder.
出处
《中国民康医学》
2008年第5期398-399,共2页
Medical Journal of Chinese People’s Health
关键词
文拉法辛
阿米替林
抑郁症
Venlafaxine
Amitriptyline
Depression disorder
