摘要
目的:探讨脉络宁注射液治疗慢性肺心病急性加重期的疗效。方法:60例患者随机分成脉络宁治疗组30例、对照组30例。对照组采用常规治疗,脉络宁治疗组在其基础上加用脉络宁注射液静脉滴注,15天为一疗程。分别检测患者治疗前后临床疗效、血液流变学与血气分析各指标变化。结果:用药前两组患者临床症状、血气指标、血液流变学差异均无统计学意义(P>0.05)。治疗后各项指标都有不同程度改善,治疗后两组相比在血液流变学指标上差异有统计学意义(P<0.01)。结论:脉络宁注射液可缓解慢性肺心病急性加重期患者的临床症状、改善血气分析指标、降低血液粘稠性,改善微循环及血液的流变性,进而改善呼吸衰竭及循环衰竭,有效改善患者的预后。
Objective： To evaluate the clinical therapeutic effect of Mailuoning injection on patients with acute exacerbation of chronic pulmonary heart disease. Methods： Sixty - four patients with acute exacerbation of chronic pulmonary heart disease were divided into the control group （30 cases）, and the treatment group （30cases） at random. The treatment group of 32 cases was treated with Mailuoning injection, in addition to routine therapy. The control group was treated with routine therapy. The treatmeat course lasted 15 days. The changes in clinical symptom,blood gas analysis and indexes of hemorheology were observed before and after treatment. Results： There was no remarkable difference in clinical symptom, blood gas analysis and indexes of hemorbeology between two groups before treatment. There was no significant improvement after treatment in the control group （ P 〉 0. 05 ） . There was remarkable improvement in clinical symptom, blood gas analysis and indexes of hemorheology in the treatment group after treatment, and there was also significantly statistical difference in the indexes of hemorheology after treatment between two groups （ P 〈 0.01 ）. Conclusion： Mailuoning injection can relieve clinical symptom of patients with acute exacerbation of chronic pulmonary heart disease, and improve microcirculation as well as respiratory and heart functions. The treatment of Mailuoning injection could improve the prognosis.
出处
《包头医学院学报》
CAS
2008年第2期140-142,共3页
Journal of Baotou Medical College
关键词
慢性肺心病
脉络宁
血气分析
血液流变学
Chronic pulmonary heart disease
Mailuoning
Blood gas analysis
Hemorheology
