期刊文献+

肿瘤基因治疗新靶点及相应治疗策略

下载PDF
导出
摘要 随着分子生物学、分子遗传学、免疫学等相关学科的发展和渗透,基因治疗特别是肿瘤基因治疗技术迅速发展,基因治疗的靶向性是值得密切关注的问题之一,如何寻找合适的靶分子是基因治疗肿瘤的重要方向。现针对研究发现的新靶点及其相应的治疗策略进行探讨。
出处 《基层医学论坛》 2008年第1期53-54,共2页 The Medical Forum
  • 相关文献

参考文献7

二级参考文献96

  • 1HongZhu Xiao-PingChen Wan-GuangZhang Shun-FengLuo Bi-XiangZhang.Expression and significance of new inhibitor of apoptosis protein survivin in hepatocellular carcinoma[J].World Journal of Gastroenterology,2005,11(25):3855-3859. 被引量:31
  • 2刘晓红,龚德军,袁扬,黄盛东.重组腺相关病毒介导红荧光蛋白在骨髓间充质干细胞的表达[J].实用医药杂志,2006,23(3):332-334. 被引量:5
  • 3Hao Deng,Ren-Liang Wu,Hong-Yan Zhou,Xuan Huang,Ying Chen,Li-Jiang Liu.Significance of Survivin and PTEN expression in full lymph node-examined gastric cancer[J].World Journal of Gastroenterology,2006,12(7):1013-1017. 被引量:27
  • 4[1]1. Feng J. Funk WD, Wang SS, et al.The RNA component of human telomerase. Science. 1995, 269(9): 1236 - 1241.
  • 5[2]Masahiro Takakura, Kyo S, Kanaya T, et al. Expression of human telomerase subuits and correlation with telomerase activity in cervical cancer.Cancer Res, 1998, 58:1558 - 1561.
  • 6[3]Pitts AE, Corey DR. Inhibition of human telomerase by 2′ - O - methy1- RNA. Proc Natl Acad Sci USA, 1998, 95(20): 11549 - 11554.
  • 7[4]Yokoyama Y, Takahashi Y, Shinohara A, et al. Attenuation of telomerase activity by a hammerhead ribozyme targeting the template region of telomerase RNA in endometrial carcinoma cells. Cancer Res, 1998, 58(23):5406 - 5410.
  • 8[5]Wan MS, Fell PL, Akhtar S. Synthetic 2′ - O- methyl - modified hammerhead ribozymes targeted to the RNA component of telomerase as sequence - specific inhibitors of telomerase activity. Antisene Nucleic Acid Durg Dev, 1998, 8(4) :309 - 317.
  • 9[6]Kushner DM, Paranjape JM, Bandyopadhyay B, et al. 2 - 5A Antisense Directed against Telomerase RNA Apotosis in Ovarian Cancer Cell. Gynecologic Oncoloy. 2000, 76:183 - 192.
  • 10[7]Kyo S, Kanaya T, Takakura M, et al. Expression of human telomerase subunits in ovarian malignant, borderline and benign tumors. Int J Cancer,1999, 80(6) :804 - 809.

共引文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部