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婴幼儿的合理用药

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摘要 婴幼儿是指从出生28d-3周岁的小儿,这个时期小儿虽然已较新生儿显著成熟,但用药并不是单纯地将成人剂量减少。因为,药物在小儿体内分布有异于成人,第一是细胞膜通透性的不同;第二是蛋白结合力的改变;第三是体液分布的差异。且上儿肝细胞酶系统发育尚不成熟,肾功能不完善,
作者 施红健
出处 《基层医学论坛》 2008年第7期269-271,共3页 The Medical Forum
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