摘要
目的分析Stargardts病(STGD)患者视网膜和脉络膜在荧光素造影检查中可能出现的异常变化。方法对65例(130眼)STGD患者行常规眼科检查及荧光素眼底血管造影(fundus fluorescein angiography,FFA)检查。结果FFA检查:所有病例黄斑部呈现斑点状透见荧光,部分带有斑点状遮蔽荧光。44眼呈现典型的"牛眼征",4眼黄斑萎缩区显露脉络膜的粗大血管,56眼黄斑区以外散在点状透见荧光,116眼呈暗脉络膜征,22眼视盘高荧光,6眼视盘分支静脉充盈迟缓,1眼可见小血管着染伴渗漏。结论根据STGD患者出现的FFA异常变化,可以初步了解其所处的病变程度,提示FFA是一种诊断STGD病的有效手段。
Objective To study the retinal and choroidal circtdation abnormality in fundus fluorescein angiography（FFA） of Stargrdts patients. Methods Routine eye examination and FFA were performed in 65 cases（ 130 eyes）. Results On FFA, dot-like transmitted fluorescences were found in macular lesions in all eyes, partially with obstructed fluorescences, typical ＂bull＇s eye＂ pattern in 44 eyes. Coarse vessels of choroid could be seen in macular lesion areas of 4 eyes. Diffused dot-like transmitted fluorescences outside macular existed in 56 eyes. A ＂ dark choroids＂ was revealed in 116 eyes. Optic disc showed hyperfluorescence in 22 eyes. Retinal venous branches showed delayed filling in 6 eyes. Retinal veins were stained with dye and showed leakage in 1 eye. Conclusion Abnormality in FFA can indicate the stage of Stargardts,and FFA is effective in the diagnosis of Stargardts disease.
出处
《眼科新进展》
CAS
2008年第4期278-281,共4页
Recent Advances in Ophthalmology
基金
国家高技术研究发展863计划项目资助(编号:2006AA02Z19D)
国家自然科学基金资助(编号:30371510)
中国科学院知识创新工程重要方向项目资助(编号:KSCX2-YW-R-72)~~
