摘要
目的监测神经外科患者临床感染病原菌流行病学分布及其耐药状况。方法收集2002年1月至2005年12月白求恩国际和平医院神经外科住院患者临床感染有关的病原学资料。结果神经外科临床感染易感部位依次为下呼吸道、中枢神经系统、泌尿道、血液。细菌学检查共检出115株细菌,以肺炎克雷伯菌(31株,27.0%)、铜绿假单胞菌(24株,20.9%)和鲍曼不动杆菌(21株,18.3%)位居前3位。革兰阴性杆菌的总体药物敏感性为:亚胺培南93.5%,哌拉西林-他唑巴坦67.3%,头孢他啶和氨曲南均为33.6%,环丙沙星26.2%,阿米卡星15.9%。结论神经外科患者临床感染以下呼吸道感染为主,革兰阴性杆菌多见,尤其是肺炎克雷伯菌、铜绿假单胞菌和鲍曼不动杆菌,其耐药性相当严重,应当引起足够重视。
Objective To determine the epidemiological distribution and antimicrobial resistance of bacteria isolated from in-patients in neurosurgical department. Methods The clinical data of pathogens isolated from in-patients in neurosurgical department of bethune international peace hospital were collected from January 2002 to December 2005. Results The susceptible infected sites for in-patients in neurosurgical department were successively lower respiratory tract, central nervous system, urinary tract and blood. A total of 115 pathogens were found in bacteriological detection. The Klebsiella pneumoniae （ 31 strains, 27.0% ）, Pseudomonas aeruginosa （ 24strains, 20.9% ） and Acinetobacter baumannii（21strains, 18.3% ） were the most common pathogens. The general antimicrobial susceptibility rate of Gramnegative bacilli was imipenem 93.5% , piperacillin-tazobatam 67.3% , ceftazidime and aztreonam 33.6% , ciprofloxacin 26.2% and amikacin 15.9%. Conclusions Lower respiratory tract infection is the common infection for in-patients in neurosurgical department at present, and the prevailing pathogens are Gram-negative bacilli, especially Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii. The isolates have the characteristics of high prevalence and multiple resistance, which should be paid more attention.
出处
《检验医学》
CAS
北大核心
2008年第2期135-137,共3页
Laboratory Medicine
基金
河北省科技攻关计划项目(042761211)
关键词
细菌
感染
耐药
神经外科
患者
Bacterium
Infection
Drug-resistance
Neurosurgical department
In-patient
