摘要
目的了解氟斑牙患者体内无机元素的含量及血氟与各元素之间的相关关系。方法在新化县燃煤型氟中毒病区3个病区乡和一个非病区乡共抽取五年级学生80名,按氟斑牙病变程度分对照组、可疑组、极轻组、轻度组、中度组和重度组。检测患儿血清钙、镁、铜、铁、锌含量,并分析血氟与无机元素间的关系。结果各组间血氟、钙、铁、锌含量筹异有统计学意义(F 值分别为17.802、5.335、14.356、2.881,P<0.05或 P<0.01),镁和铜含量差异无显著性意义(P>0.05)。随氟斑牙病情加重,钙、锌逐渐降低而铁逐渐升高。血氟与钙、锌呈负相关(r 分别为-0.687、-0.563,P<0.01),与铁呈正相关(r=0.464,P<0.01)。结论氟斑牙患儿体内存在无机元素钙、铁、锌的代谢紊乱。
Objective To detect mineral element levels in children with dental fluorosis and to study the relations between serum fluoride and mineral elements. Methods 80 children in Grade 5 were chosen from three coal - burning fluorosis areas and one non - fluorosis area in Xinhua County, Hunan Province. They were divided into six groups by the seriousness of the dental fluorosis： control group, doubtful group, very light group, light group, medium group and severe group. The content of fluoride, calcium, magnesium, copper, iron, zinc in serum was detected. The correlations between serum fluoride and those elements were analyzed. Results In different groups, concentration of serum fluoride, calcium, iron, zinc was significantly different （ F was 17. 802, 5. 335, 14. 356, 2. 881 respectively, P 〈 0.05 ＆ P 〈 0.01 ） and that of serum magnesium, copper had no significant difference （ P 〉 0.05 ）. The levels of calcium, zinc showed descendent trend while the levels of iron tended to increase with seriousness of dental fluorosis. There was a negative correlation between the content of fluoride and calcium, zinc in serum（ r was -0.687, -0.563 respectively, P 〈 0.01 ）. The serum fluoride and iron were positive correlativity（ r = 0. 464,P 〈 0.01 ）. Conclusions There is a disorder of mineral elements such as calcium, iron, zinc in children with dental fluorosis.
出处
《中国地方病防治》
北大核心
2008年第2期111-113,共3页
Chinese Journal of Control of Endemic Diseases
关键词
氟中毒
氟斑牙
化学元素
相关关系
Endemic fluorosis
Dental fluorosis
Mineral elements
Correlation
