期刊文献+

发光二极管应用于光动力学疗法的可行性分析 被引量:6

Feasibility of light-emitting-diode applied to photodynamic therapy
原文传递
导出
摘要 讨论了发光二极管(Light-emitting-diode,LED)在航天医学中作为激光器的替代光源用于光动力学疗法(Photodynamic therapy,PDT)的可行性。分析了发光二极管用于光动力学疗法的优势,介绍了LED用于不同类型光敏剂进行PDT治疗的实验研究,概括了LED-PDT治疗系统在国内外的研制现状。说明了LED替代激光器作为PDT的激发光源是可行的。LED作为我国航天医学领域中的一种重要光源,为维护航天员的健康将会发挥重要作用。 The feasibility of light-emitting-diode(LED)applied to Photodynamic therapy(PDT)instead of laser in the field of space medicine is analyzed.The typical advantages of LED applied to PDT are introduced.Some experimental results show that LED can be used to PDT for various photosensitizers.The current situation of LED-PDT medical apparatus is mentioned.It is feasible that LED is used as the light source of PDT instead of laser.LED is a significant light source in the field of space medicine and plays a key role on the astronaut healthy support.
出处 《光学技术》 EI CAS CSCD 北大核心 2008年第2期265-268,共4页 Optical Technique
基金 国家自然科学基金资助项目(20505002) 北京市优秀人才培养计划资助项目(20071D1600300394) 北京理工大学优秀青年教师资助项目(000Y06-23)
关键词 发光二极管 光动力学疗法 光敏剂 航天医学 light-emitting-diode photodynamic therapy photosensitizer space medicine
  • 相关文献

参考文献15

  • 1Whelan HT, Buchmannla EV, Whelan NT. NASA light emitting diode medical applications from deep space to deep sea[A]. Space Technology and Applications International Forum [ C]. Melville, New York: American Institute of Physics, 2001.
  • 2Dougherty TJ. Photodynamie therapy [ J ]. Photochem Photbiol, 1993, 58: 895-900.
  • 3Weishaupt KR, Comer CJ, Dougerthy TJ. Identification of singlet oxygen as the cytotoxic agent in the photoactivation of a murine tumor[J]. Cancer Re.s, 1976, 36: 2326-2329.
  • 4Brancaleon L, Moseley H. Laser and non-laser light sources for photodynamic therapy[J]. Lasers Med Sci, 2002, 17: 173-186.
  • 5方志烈.发光二极管材料与器件的历史、现状和展望[J].物理,2003,32(5):295-301. 被引量:42
  • 6Szeimies RM, Hein R, Baumler W, et al. A possible new incoherent lamp for photodynamic treatment of superficial skin lesions [J]. Acta Derm Venereol (Stockh), 1994, 74: 117-119.
  • 7Stringer MR. Letters to the Editor : Problems associated with the use of broad- band i lluminationsources for photodynamic therapy [J]. Physics in Medicine and Biology, 1995, 40: 1733-1735.
  • 8Whelan HT, Houle JM, Bajic DM, et al. Benzoporphyrin Deriva tive and Light Emitting Diode for Use in Photodynamic Therapy Applications of Space Light Emitting Diode Technology. Space[J ] Technology and Applications International Forum, 1998, 420 729-735.
  • 9Whelan HT, Houle JM, Donohoe DL, et al. Medical applications of space light -emitting diode technology space station and beyond [J]. Space technology and applications international forum, 1999, 458: 3-15.
  • 10Macecek J, Kolarova H, Bajgar R, et al. Comparison of light emitting diodes and semiconductor laser inducing photodynamic therapy of cancer cells [ J ]. Proc of SPIE, 2007, 6604 (2J) : 66042J-1-66042J-5.

二级参考文献15

  • 1Craford M G, Holonyak N Jr, Kish F A. Sci. Am. , 2001,284:63.
  • 2Wierer J J et al. Appl. Phys. Lett. , 2001,78:3379.
  • 3Kish F A et al. Appl. Phys. Lett., 1994, 64:2839.
  • 4Krames M R et al. Appl. Phys. Lett. , 1995, 75:2365.
  • 5Holonyak N Jr, Bevaqua S F. Appl. Phys. Lett. , 1962, 1:82.
  • 6Niina T. J. Electrochem. Soc. , 1977, 124(8) :1285.
  • 7Lorimor O G. J. Elechochem. Soc., 1975, 122(3):407.
  • 8Craford M G. IEEE. Trans. E.D. , 1977, 24:935.
  • 9Nishizawa J, Suto K. J. Appl. Phys. , 1977,48:3484.
  • 10Tang C W, Van Slyke S A. Appl. Phys. Lett., 1987, 51:913.

共引文献41

同被引文献65

引证文献6

二级引证文献45

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部