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糖尿病酮症酸中毒合并血淀粉酶升高的相关因素分析

Risk factors of hyperamylasemia in diabetic ketoacidosis
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摘要 分析152例糖尿病酮症酸中毒(排除急性胰腺炎所致)患者血淀粉酶(AMY)升高的相关因素,以血AMY为因变量,以入院时14项生化指标为自变量进行多元线性回归分析。血葡萄糖、钠、渗透压、甘油三酯进入回归方程,偏回归系数分别为10.26,10.35,2.21和8.00,常数为-2162.06。与269例血AMY正常者血葡萄糖、甘油三酯、钠、渗透压水平比较,差异有统计学意义(P〈0.05)。 Risk factors of hyperamylasemia in 152 diabetic ketoacidosis (DKA) patients who had no acute pancreatitis were examined. Serum levels of hemodiastase, natrium, kalium, chlorine, calcium, phosphonium, creatinine, carbon dioxide combining power, osmotic pressure, blood glucose, blood lipids and uric acid were measured. With hemodiastase and other 14 factors as independent variables, the multiple linear regression analysis was performed and the partial regression coefficient was estimated. Blood glucose, serum natrium, osmotic pressure and triglyceride entered the regression equation, and their partial coefficients were 10.26, 10.35, 2.21 and 8.00, respectively. The constant quantity was - 2162.06. Compared with amylase-normal group, hyperamylasemia group showed statistically significant difference in blood glucose, serum natrium, osmotic pressure and triglyceride levels. Higher blood glucose and triglyceride might be the primary causes of hyperamylasemia.
出处 《中华全科医师杂志》 2008年第4期264-265,共2页 Chinese Journal of General Practitioners
关键词 糖尿病酮症酸中毒 血淀粉酶升高 相关因素 预后 Diabetic ketoacidosis Amylases
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参考文献4

  • 1中华医学会消化病学分会胰腺疾病学组.中国急性胰腺炎诊治指南(草案)[J].中华消化杂志,2004,24(3):190-192. 被引量:1765
  • 2Takahashi J, Nishijima K, Shukunami K, et al. Flare-up of serum amylase prior to onset of lethal ketoacidosis in a patient with fulminant type 1 diabetes. Diabetes Care ,2006,29:461-462.
  • 3Vantyghem MC, Haye S, Balduyck M, et al. Changes in serum amylase, lipase and leukocyte elastase during diabetic ketoacidosis and poorly controlled diabetes. Acta Diabetol, 1999,36:3944.
  • 4Halonen KI, Pettila V, Leppaniemi AK, et al. Multiple organ dysfunction associated with severe acute pancreatitis. Critlare Med, 2002,30 : 1274-1279.

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