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胺碘酮治疗冠心病急性心肌梗死伴高危快速型心律失常的有效性和安全性的研究 被引量:21

Study of Effect and Security of Amiodarone on Treating Tachyarrhythmia in Acute Myocardial Infarction
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摘要 目的:探讨胺碘酮对急性心肌梗死伴高危快速型心律失常的有效性和安全性。方法:2004年2月2007年8月我院急诊抢救室、冠心病重症监护室收治急性心肌梗死伴高危快速型心律失常235例,分室上性(AV)组和室性(V)组,AV组分为治疗(AVA)组和对照(AVC)组,AVA组予以胺碘酮,AVC组予以普罗帕酮治疗。V组亦分为治疗(VA)组和对照(VC)组,AVA组予以胺碘酮,AVC组予以利多卡因治疗。通过临床治疗比较治疗组和对照组的有效性和安全性。结果:治疗组(AVA+VA)总有效率89.1%,而对照组(AVC+VC)65.5%,两组相比差异显著。结论:急性心肌梗死伴高危快速型心律失常时静脉注射胺碘酮能有效予以控制。 Objective:To explore the effect and security of Amiodarone on tachyarrhymia in acute myo- cardial infarction. Methods: Two hundreds and thirty - five patients were divided into two groups : supravent- ricular tachyarrhythmia group ( AV ) and ventricular tachyarrhythmia ( V ). AV was treated with Amiodarone as group AVA, and treated with Propafenone as group AVC. V was treated with Amiodarone as groups VA, while treated with Lidocaine as group VC. Effect and security were recorded. Results:The effective rate treated by Amiodarone ( AVA + VA ) was 89.1%. The effective rate of control groups was 65.5%. It had significant difference between two groups. Conelusion:Amiodarone used to treated tachyarrhymia in acute myocardial infarction can be more effective and securely.
出处 《河北医学》 CAS 2008年第3期303-306,共4页 Hebei Medicine
关键词 胺碘酮 急性心肌梗死 心律失常 Amiodarone Acute myocardial infarction Arrhythmia
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  • 1Greene HL,Roden DM,Katz RJ,Woosley RL,Salerno DM,Henthorn RW.The Cardiac Arrhythmia Suppression Trial:first CAST then CAST II[J].J Am Coll Carciol,1992,19∶894-898.
  • 2Podrid PJ.Amiodarone:reevaluation of an old drug[J].Ann Intern Med,1995,122∶689-700.
  • 3Roden DM.Pharmacokinetics of amiodarone:implications for drug therapy[J].Am J Cardiol,1993,72∶45F-50F.
  • 4Singh BN,Venkatesh N,Nademanee K,et al.The historical development,cellular electrophysiology,and pharmacology of amiodarone[J].Prog Cardovasc D S,1989,31∶249-280.
  • 5Singh BN,Nademanee K.Amiodarone and thyroid function:clirical implications during antiarrhythmic therapy[J].Am Heart J,1983,106∶857-869.
  • 6Nattle S.Comparative mechanisms of action of antiarrhythmic drugs[J].Am J Cardiol,1993,72(16)∶13F-17F.
  • 7The CASCADE investigators:The Cascade study-randomized anti-arrhythmic drug therapy in survivors of cardiac arrest in Seattle[J].Am J Cardiol,1993,13∶442-449.
  • 8Levine JH,Massumi A,Scheinman MM,et al.Intravenous amiodarone for recurrent sustained hypotensive ventricular tachyarrhythmias.The Intravenous Amiodarone Multicenter Trial Group[J].J Am Coll Cardiol,1996,27∶67-75.
  • 9Kowey PR,Levine JH,Herre JM,et al.Randomized,double-blind comparison of intravenous amiodarone and bretylium in the treatment of patients with recurrent,hemodynamically destabilizing ventricular tachycardia or fibrillation.The Intravenous Amiodarone Multicenter Investigators Group[J].Circulation,1995,92∶3255-3263.
  • 10Scheinman MM,Levine JH,Cannom DS,et al.Dose-ranging study of intravenous amiodarone in patients with life-threatening ventricular tachyarrhythmias.The Intravenous Amiodarone Multicenter Investigators Group[J].Circulation,1995,92∶3264-3272.

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