摘要
目的探讨呼吸系统疾病发生真菌感染的相关因素,为临床呼吸系统疾病真菌感染的预防和治疗提供参考依据。方法对呼吸系统疾病患者进行痰液真菌培养后,明确了真菌感染患者144例。分析呼吸系统不同疾病真菌感染的构成比,呼吸系统疾病真菌感染与年龄、病程、抗生素应用的相关性。结果144例呼吸系统疾病真菌感染患者中,不同疾病真菌感染的构成比为慢性支气管炎(42.4%)>肺肿瘤(25.7%)、肺源性心脏病(16.0%)>肺气肿(9.7%)、肺炎(6.2%),各组间有明显差异性(P<0.05);年龄≥60岁的为67.1%,年龄<60岁的为31.9%,两组间有显著性差异(P<0.01);原发疾病病程≥6个月的为72.9%,原发疾病病程<6个月的为27.1%,两组间有显著性差异(P<0.01);真菌培养前应用抗生素≥2周的为93.7%,应用抗生素<2周的为6.3%,两组间有显著性差异(P<0.01)。结论呼吸系统疾病真菌感染的特点是易发生于老年人、慢性疾病、抗生素应用不当的患者;发生真菌感染的主要因素是临床医师使用抗生素的指征掌握不严、细菌培养意识淡薄、预防性抗生素的应用、滥用激素、恶性肿瘤的放化疗。
Objective To study the correlation factor of fungus infection from respiration system diseases and provide reference rationale for the prevention and treatment of clinical respiratory system diseases fungus infection. Method We culture sputum fungus for re- spiratory system diseases patients,unambiguou fungus infection patients are 144 cases, analyse the composing ratio of respiratory system different diseases fungus infection ,the relativity of fungus infection of respiratory diseases and age,course of diseases,antibiotic application. Result In 144 cases respiratory system diseases fungus infection patients,the composing ratio of different diseases fungus infection is chronic bronchitis tracheitis（42.4% ） 〉 lung tumor（25.7% ） ,cor pulmonale（ 16.0% ） 〉 emphysema（9.7% ） ,pneumonia（6.2% ） ,every group has obvious difference（ P 〈 0.05 ） ;age ≥ sixty is 67.1% , age 〈 sixty is 31.9% , the two groups have obvious difference（ P 〈 0.01 ） ; idiopathy course of diseases ≥ six months is 72.9% ,idiopathy course of diseases 〈 six months is 27.1% , the two groups have obvious difference （ P 〈 0.01 ） ; apply antibiotic before fungus culture ≥ two weeks is 93.7% , apply antibiotic 〈 two weeks is 6.3% , the two groups have obvious difference （P 〈 0.01 ）. Conclusion The characteristic of respiratory system diseases fungus infection is easy to happen to the elderly ,chronic disease ,antibiotic application improper patients;the main factor of fungus infection is clinical physician use antibiotic indication master relaxed ,bacteria culture consciousness become indifferent,the application of preventive antibiotic,misuse hormone, the radiotherapy and chemotherapy of malignancy.
出处
《医学研究杂志》
2008年第4期86-87,共2页
Journal of Medical Research
关键词
呼吸系统疾病
真菌
感染
痰
Respiratory system diseases
Fungus
Infection
