摘要
目的研究和探讨动脉化疗栓塞（TACE）治疗肝脏转移性肿瘤时造成的胆道损伤的原因以及治疗和预防。方法2001-2006年，笔者对6例因反复TACE引起的胆道损伤的肝脏转移性肿瘤病人的临床及影像资料进行了回顾性分析。结果6例病人接受了数次TACE治疗后的2周至2个月内均出现了严重的胆道损伤，影像表现主要为局限或多发的肝管扩张、胆汁瘤形成、损伤区肝实质萎缩。结论TACE治疗少动脉血供的转移性肝脏肿瘤时可导致严重的胆道缺血性损伤，对此类肿瘤的介入治疗要慎重。
Objective To study the pathogenesis, treatment and prevention of TACE （transcatheter arterial chemoembolization） induced bile duct damage for metastatic liver lesions. Method During 2001-2006, 6 patients withdiffent metastatic liver lesions had developed TACE-induced bile duct injuries. Clinical and imaging findings were retrospectively reviewed. Results All cases were found to have destructive demage of intraheptic bile duct from 2 weeks to 3 months after several TACE treatments. Focal or multiple bile duct dilatation, biloma, progressive atrophy of the corresponding he- patic parenchyma were found on image examination. Conclusion TACE therapy of metastatic liver lesions with low-arterial blood supply may result in severe biliary damage and its indiscriminate use should be prohibited.
出处
《中华肝胆外科杂志》
CAS
CSCD
2008年第3期167-169,共3页
Chinese Journal of Hepatobiliary Surgery
关键词
肝肿瘤
动脉化疗栓塞术
并发症
胆道损伤
Liver neoplasm, Transcatheter arterial chemoembolization
ComplicationBile duct injury
