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电针对不同证型不孕症患者体外受精-胚胎移植作用的研究 被引量:22

Effects of electroacupuncture on in vitro fertilization and embryo transplantation in the patient of in-fertility with different syndromes
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摘要 目的:探讨电针对体外受精-胚胎移植(IVF-ET)的适宜证型。方法:在配合电针干预进行IVF-ET的不孕症患者中选取肾虚型(A组)52例、肝郁型(B组)44例、痰湿型(C组)30例,3组患者均为长方案超促排卵,在控制性超排卵前及超排卵过程中配合应用电针,观察3种证型不孕症患者的受精率、种植率和临床妊娠率。结果:A组受精率、种植率、临床妊娠率分别为81.3%、23.5%、44.1%,B组分别为80.5%、27.8%、46.5%,2组均显著高于C组的71.9%、17.1%、32.7%(P<0.05);B组优质胚胎率为70.7%,显著高于C组的57.9%(P<0.05),A组高于C组,但无统计学意义;3组患者基础情况、促性腺激素(Gn)用量、Gn用药时间、人绒毛膜促性腺激素注射日血雌二醇水平、获卵数、卵裂率、移植胚胎数差异均无显著性意义。结论:在体外受精-胚胎移植中的电针治疗对肾虚型及肝郁型不孕症患者较痰湿型效果好。 Objective To probe into effects of electroacupuncture (EA) on in vitro fertilization and embryo transplantation (IVF-ET) in the patient of infertility with different syndromes. Methods Among the 126 patients of infertility who received EA for IVF-ET, 52 cases of kidneydeficiency type (group A), 44 cases of the liver-qi stagnation type (group B) and 30 cases of phlegm-dampness type (group C) were selected. All of them in the 3 groups were treated with EA before and during controlled ovarian hyper-stimulation, and the effects of EA on the patients in the 3 groups were investigated. Results The fertility rate, implantation rate and clinical pregnancy rate were 81.3%, 23.5%, 44. 1% in group A, 80.5%, 27. 8%, 46.5% in group B and 71.9%, 17, 1%, 32.7% in group C, respectively, group A and B being better than group C (P〈0.05); the good quality embryo rate of 70, 7% in group B was significantly higher than 57.9% in group C (P〈0.05) ; there were no significant differences in patient's basal condition, the dosage and administration time of gonadotropin, and blood level of estradiol on the day of injection of human ehorionie gonadotropin, the number of gained ooeytes, ooeyte cleavage rate and the number of transplantation embryo among the 3 groups, Conclusion Clinical effects of EA treatment on IVF-ET in the infertility patients of kidney deficiency type and the patients of the liver-qi stagnation type are better than that in the patients of phlegm-dampness type.
出处 《中国针灸》 CAS CSCD 北大核心 2008年第4期254-256,共3页 Chinese Acupuncture & Moxibustion
关键词 电针 受精 体外 胚胎植入/针灸效应 不育 女性/针灸疗法 辨证论治 Electroacupuncture Fertilization in Vitro Embryo Implantation/am eff Infertility, Female/am ther Syndrome Differ Treatment
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