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儿童手足口病31例临床分析 被引量:3

Clinical Analysis of 31 Children with Hand-Foot-Mouth Disease
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摘要 目的总结交流儿童手足口病临床诊治经验。方法对2007年4月至2007年6月诊治的31例小儿手足口病的流行病学、临床特征和治疗转归进行回顾性分析。结果?31例患儿中20例为托幼机构患儿,18例有明确手足口病接触史。平均年龄2.8岁。所有病例均有口腔粘膜溃疡性疱疹及四肢末端水疱样皮疹等典型临床症状和体征。经及时诊断和利巴韦林等早期治疗后,均获痊愈。未出现严重并发症。结论儿童手足口病只要及时、早期治疗,给予重视,预后良好。在托幼机构和小学校做好隔离和预防工作,对减少本病的发生和流行十分重要。 Objective To share the experience of the diagnosis and treatment of children with hand-foot-mouth disease. Methods We retrospectively analyzed 31 children with hand-foot-mouth disease in our hospital from April 2007 to June 2007 in terms ofepidemiology, clinical features, treatment and prognosis. Results The average age of the children was 2.8 years, and 20 out of the 31 cases were from nurseries and kindergartens. Eighteen had clear contact history. Typical signs and symptoms, including oral ulcerative herpes and blister-like rash in extremities, were found in all cases. All the children were cured after timely diagnosis and early treatment with ribavirin, without any severe complications. Conclusion Timely treatment based on early diagnosis and considerate care are important for children with hand-foot- mouth disease. Nurseries, kindergartens and primary schools should attach great importance to relevant prophylaxis and isolation. These are essential for reducing the occurrence and prevalence of this disease.
出处 《中国循证医学杂志》 CSCD 2008年第4期294-295,共2页 Chinese Journal of Evidence-based Medicine
关键词 手足口病 临床特征 治疗 Hand-foot-mouth disease Clinical feature Treatment
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参考文献3

  • 1杨智宏,朱启镕,李秀珠,王晓红,王建设,胡家瑜,唐伟,崔爱利.2002年上海儿童手足口病病例中肠道病毒71型和柯萨奇病毒A组16型的调查[J].中华儿科杂志,2005,43(9):648-652. 被引量:636
  • 2Hsueh C, Jung SM, Shih SR, et al. Acute encephalomyelitis during an outbreak of enterovirus type 71 infection in Taiwan: report of an autopsy case with pathologic, immunofluorescence ,and molecular studies. Mod Pathol, 2000, 13(11): 1200-1205.
  • 3Chang LY, Hsia SH, Wu CT, et al. Outcome of infections with or without stage-based management: 1998 to 2002. Pediatric In-fectious Disease Journal, 2004, 23(4): 327-332.

二级参考文献13

  • 1刘湘云.肠道病毒感染[A].见: 胡亚美 江载芳 主编.实用儿科学 第7版[C].北京: 人民卫生出版社,2002.802-810.
  • 2叶铁真.病毒性脑炎[A].见: 吴梓粱 主编.小儿内科学 第1版[C].河南: 郑州大学出版社,2003.2239-2240.
  • 3Yan JJ, Su IJ, Chen PF, et al. Complete genome analysis of enterovirus 71 isolated from an outbreak in Taiwan and rapid identification of enterovirus 71 and coxsackievirus A16 by RT-PCR. J Med Virol, 2001,65:331-339.
  • 4Oberste MS, Maher K, Kilpatrick DR, et al. Molecular evolution of the human enteroviruses: correlation of serotype with VP1 sequence and application to picornavirus classification. J Virol, 1999,73:1941-1948.
  • 5Oberste MS, Maher K, Kilpatrick DR, et al. Typing of human enteroviruses by partial sequencing of VP1. J Clin Microbiol, 1999,37:1288-1293.
  • 6Ho M, Chen ER, Hsu KH, et al. An epidemic of enterovirus 71 infection in Taiwan. N Engl J Med, 1999,341:929-935.
  • 7Brown BA, Oberste MS, Alexander JP Jr, et al. Molecular epidemiology and evolution of enterovirus 71 strains isolated from 1970 to 1998. J Virol, 1999,73:9969-9975.
  • 8McMinn P, Lindsay K, Perera D, et al. Phylogenetic analysis of enterovirus 71 strains isolated during linked epidemics in Malaysia, Singapore, and Western Australia. J Virol, 2001,75:7732-7738.
  • 9Cardosa MJ, Perera D, Brown BA, et al. Molecular epidemiology of human enterovirus 71 strains and recent outbreaks in the Asia-Pacific region: comparative analysis of the VP1 and VP4 genes. Emerg Infect Dis, 2003,9:461-468.
  • 10Chang LY, Lin TY, Huang YC, et al. Comparison of enterovirus 71 and coxsackie-virus A16 clinical illnesses during the Taiwan enterovirus epidemic, 1998. Pediatr Infect Dis J, 1999,18:1092-1096.

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