摘要
在微波辐射下,对甲苯磺酸作催化剂,不用溶剂合成环己酮1,2-丙二醇缩酮,考察酮醇物质的量比、催化剂用量、微波功率和辐射时间对产品收率的影响.结果表明,合成该缩酮的最佳工艺条件为:n(环己酮)∶n(1,2-丙二醇)=1∶1.6,催化剂用量为反应物总质量的0.5%,辐射功率为350 W,辐射时间为3 min.在此条件下,缩酮收率可达78.0%.
Cyclohexanone 1,2-propanediol ketal was synthesized from cyclohexanone and 1,2-propanediol using p-toluene sulphonic acid as catalysts without solvent under microwave irradiation. The effects of reactant ratio, amount of catalyst, microwave irradiation power and microwave irradiation time on the yield of cyclohexanone 1,2-pmpanediol ketal were studied. The optimal conditions for the synthesis were as follows： n （cyclohexanone） ： n （1,2-pmpanediol） = 1：1. 6,mass ratio of catalyst to reactant 0.5%, microwave irradiation power 350W and radiation time 3min. Under these conditions, the yield of cyclohexanone 1,2-pmpanediol ketal could reach 78.0%.
出处
《吉首大学学报（自然科学版）》
CAS
2007年第6期102-104,共3页
Journal of Jishou University(Natural Sciences Edition)
基金
国家自然科学基金资助项目(20572021)
关键词
环己酮1
2-丙二醇缩酮
对甲苯磺酸
微波合成
cyclohexanone 1,2-propanediol ketal
p-toluene sulphonic acid
microwave synthesis
