摘要
目的研究重症急性胰腺炎(SAP)死亡病例的临床表现特点及死亡相关因素的分析。方法回顾性研究105例SAP患者临床资料,比较死亡组与存活组的临床表现特点,并采用非条件Logistic回归分析死亡相关因素。结果死亡组出现体温≥38.5℃,低氧血症、休克、白细胞计数≥15×109/L,血清钙降低,多器官功能障碍综合征(MODS)的百分率均明显高于存活组,死亡组胰腺Balthazar CT评分也高于存活组。结论SAP死亡病例具有全身炎症反应重、胰腺病变程度严重及MODS发生率高的特点。与SAP死亡相关的因素有低氧血症,MODS及胰腺病变程度。
Objective To study the clinical characteristics of fatal cases of severe acute pancreatitis （SAP） and analyze the related factors causing death of patients with SAP. Methods Clinical data of 105 cases of SAP were retrospectively reviewed and studied, the clinical characteristics and manifestations of SAP in fatal cases were compared with those of survival cases, and their death related factors were analyzed by applying non - conditional Logistic regression analysis. Results Body temperature≥38.5℃ ,low oxygenated blood, shock ,white blood cell count≥ 15 × 10^9/L and reduced serum level of calcium were usually seen in group of fatal patients and the percentage of multiple organ dysfunction syndrome（MODS） in patients of this group was obviously higher than that of patients in survival group, Balthazar CT grading in patients of fatal group was also higher than that of patients in survival group. Conclusion Fatal cases of SAP axe characterized by severe SIRS, severe pathological changes in pancreas, and high incidence of MODS, The factors related to death were hypoxemia, MODS and higher Balthazar CT grade.
出处
《临床和实验医学杂志》
2008年第4期117-117,120,共2页
Journal of Clinical and Experimental Medicine
关键词
重症急性胰腺炎
死亡
临床特点
相关因素
Severe acute pancreatitis
Death
Clinical characteristics
Factors.
