摘要
目的：研究十二指肠球部溃疡和慢性浅表性胃炎患者胃液的ＮＯ水平，以及胃液ＮＯ水平与幽门螺杆菌（ＨＰ）感染的可能联系。方法：通过胃镜，抽取２３例十二指肠球部溃疡患者、２１例慢性浅表性胃炎患者和１９例正常人的胃液。用Ｇｒｉｅｓ法测胃液中ＮＯ水平。结果：十二指肠球部溃疡患者胃液ＮＯ水平是（３５．５６±６．１５μｍｏｌ／Ｌ），ＨＰ感染者是（３４．１２±８．１０μｍｏｌ／Ｌ）。两者显著高于正常个体（１８．６０±３．０７μｍｏｌ／Ｌ）。慢性浅表性胃炎患者（１９．７３±２．３２μｍｏｌ／Ｌ）和ＨＰ阴性者（２０．２６±３．４４μｏｍｌ／Ｌ）胃液中ＮＯ水平（Ｐ＜０．０１）。结论：结果提示ＮＯ可能是引起十二指肠球部溃疡的一个因素。
Aims:To study the nitric oxide(no) level in gastric juice of patients with duodenal ulcer and chronic superficial gastritis and the possible relation of NO in gastric juice and HP infection.Methods:The gastric juice were taken from 23 patients with duodenal ulcer,21 chronic superficial gastritis and 19 healthy individual through the endoscope,NO level in gastric juice was measured by Griess method.Results:The results showed that NO levels in gastric juice of the patients with duodenal ulcer(35.56±6.15 umol/L) and with Hp positive(34.12±8.10 umol/L)were significantly higher than those of healthy individuals(18.60±3.07 umol/L),the patients with chronic superfical gastritis(19.73±2.32umol/L) and HP negative(20.26±3.44umol/L)(P<0.01)Conclusion:The results suggested that NO could be a factr for causing the duodenol ulcer,Hp infection may be the cause of NO elevation in the gastric juice.
出处
《胃肠病学和肝病学杂志》
CAS
1997年第2期116-118,共3页
Chinese Journal of Gastroenterology and Hepatology
关键词
一氧化氮
胃液
十二指肠溃疡
浅表性胃炎
Nitric oxide,gastric juice Hp,duodenal ulcer chronic surfacial gastritis.
