摘要
目的观察人工合成医用硫酸钙和磷酸钙在骨创伤中,作为骨替代物的临床疗效。方法对50例创伤骨折并存在骨缺损者,治疗除采用内固定(钢针、钢板)和外固定(石膏、外固定架)外,结合使用医用硫酸钙组24例,使用医用磷酸钙组26例。结果所有使用填充人工骨的病例,骨折均如期愈合,平均愈合时间11周(8～16周),使用硫酸钙者未出现任何异常反应和并发症,使用磷酸钙者有2例浅表渗出,经换药愈合。平均随访时间24周(16～50周),硫酸钙组平均吸收时间较磷酸钙组短约30周。结论医用硫酸钙和磷酸钙人工骨均可作为骨替代物应用,在辅助固定下具有安全,方便,副作用小以及填充效果确实,骨折愈合良好等优点。硫酸钙骨粉固化后较磷酸钙坚固,具有较强支撑作用。在内或外固定确实的情况下,二者均不失为治疗骨缺损的最佳选择。
Objective To observe the curative effect and difference between calcium sulfate and calcium phosphate as bone substitutions in traumatic fractures. Methods Fifty cases （26 with Colle＇s fractures and 24 with calcaneus＇s frac-tures） were treated with internal and external fixation, and filled bone defect with bone substitutions. Calcium sulfate was used for 24 cases and calcium phosphate for 26. Results All fractures that filled with bone substitutions were healed well. Average healing time was 11 weeks. Two cases used the calcium phosphate were effusion in local soft tissue and change dressing. The mean period of follow-up was 24 （16 ～ 50） weeks. The bone substitutions were absorbed completely. The absorptive of calcium sulfate was faster then calcium phosphate cement. Conclusion The advantages of calcium sulfate and phosphate as the bone substitutions are safety, convenience, and less side effect, fill certainly better and fractures healed well. The calcium sulfate powder of the total had better supporting for bone defect area after solidification, and it operated easily. Both of the calcium sulfate and phosphate can be the suitable bone substitutions for bone defect in traumatic fractures under the effective fixation.
出处
《生物骨科材料与临床研究》
CAS
2008年第2期33-36,共4页
Orthopaedic Biomechanics Materials and Clinical Study
关键词
骨替代物
医用硫酸钙
医用磷酸钙
Bone substitutions Calcium sulfate Calcium phosphate
