摘要
目的探讨脑利钠肽(BNP)对老年心力衰竭患者的预后价值。方法纳入62例确诊的老年心衰患者于入院及出院前监测BNP水平,并用彩色多普勒测定其左室射血分数(LVEF),随访出院后患者主要心血管事件的发生情况。结果在未发生心血管事件组,BNP水平较入院明显降低(P=0),其中半数降至正常;在发生心血管事件组,7例患者BNP水平较入院时升高,余10例患者BNP水平较入院时明显降低(P=0.03),但均未降至正常;死亡组与非死亡组治疗后相比,死亡组BNP水平明显高于非死亡组(P=0.002)。结论动态观察BNP有利于判断心衰患者预后,BNP水平越高预后越差,治疗后BNP反而升高者预后极差。
Objective To explore the value of brain narriureric peptide （BNP） in the prognosis of heart failure in eldly patients. Methods Plasma of BNP were measured in 62 patients with heart failure on admission and discharge, left ventrieular ejection fraction was determined by echocardiography. All patients were followed up to investigate the clinical main adverse cardiac events （MACE）. Results The plasma of BNP were significant degrade comparing with admission in the Non-MACE group （P=0） ; in the group that suffered from cardiac death, the levels of BNP were elevated in 7 patients, and other 10 patients were significant degraded （P=0.03）, but did not down to normal. The plasma of BNP in MACE group was significant higher than non-MACE after therapy. Conclusions Observation the changes of the plasma BNP was benefical to the prognosis of heart failure： the higher the level of BNP. the worse of prognosis; the prognosis was worst when the plasma of BNP elevated after therapy.
出处
《福建医药杂志》
CAS
2008年第2期8-10,共3页
Fujian Medical Journal
关键词
脑利钠肽
心力衰竭
预后
老年
Brain natriuretic peptide
Heart failure
Prognosis
Elderly
