摘要
目的:提高小儿感冒颗粒质量标准。建立薄荷中薄荷脑、广藿香中百秋李醇的定性鉴别。方法:采用气相色谱法,色谱条件,聚乙二醇以(PEG)-20 M 为固定液,涂布浓度为10%,柱长为2 M,采用程序升温。百秋李醇;初始温度100℃,保持5 min,以10 ℃·min^(-1)的速度升温至120℃,保持10min,再以10℃·min^(-1)升温至140℃保持5 min:。薄荷脑;初始温度140℃,保持5min 后,以40℃·min^(-1)升温至180℃,保持15 min,进样体积均为5μL,使用氢火焰离子检测器。结果:检出薄倚脑和百秋李醇。结论:本方法准确,灵敏度高,可用于小儿感冒颗粒质量标准控制。
Objective ：To establish the method for quality control of Xiao er Gan mao granules. Methods： Menthol in the Herba Menthae and pathocohol in the cablin patchoali were identified by gas chromatographic, using a column packed with PEG -20 M as stationary phase. Concentration is 10%. The column length was 2 M. Nitrogen gas was used as carrier gas and FID . Patchoulialeoho;The column is gradiently raised with initial temperature at 100℃, sustained for 5 min,then raised to 120℃,at the rate of 10℃·min^-1,sustained for 10 rain,then raised to 140 at the rate of 10℃·min^-1 sustained for 10 min. Menthol：The column temperature by programming controller;The column is gradlently raised with initial temperature at 140℃ ,sustained for 5 min,then raised to 180℃ ,At the rate of 40 ℃·min^-1 sustained for 15 min. Results：com out patchoulialeoho and Mentho be deteced by gas chromato- graphic. Conclusion：The method is accurate. ,rapid and simple,It can be applied for the quality control of Xiao er Gan mao granules.
出处
《药物分析杂志》
CAS
CSCD
北大核心
2008年第3期480-482,共3页
Chinese Journal of Pharmaceutical Analysis
关键词
薄倚脑
百秋李醇
气相色谱法
menthol
patchoulialeoho
gas chromatographic
