摘要
目的研究ICU病区的病原菌的来源、分布特点及耐药情况。方法收集2004-01-2007-06 147例NP患者,研究其病原菌群特点及耐药性,并对病原菌结果进行对比分析。结果NP的病原菌主要为G-菌（70.4%）,其中鲍曼不动杆菌、铜绿假单胞菌、阴沟肠杆菌为主,亚胺培南、氨曲南G-菌耐药低;G＋菌（18.6%）以葡萄球菌为主,对万古霉素敏感;真菌感染占11.2%,多种抗生素耐药。结论NP病原菌以G-菌为主,且耐药情况严重。G-菌感染对亚胺培南敏感,G＋菌对万古霉素敏感,动态监测细菌耐药性,合理选择抗生素。
Objective To investigate the distribution of pathogens and their antibiotic resistance in the patients with lower respiratory tract infection in intensive care unit. Method The clinical data, bacterial spectrum and drug resistance of intensive care unit patients from January 2004 to June 2007 were analyzed retrospectively. Results A total of 147 pathogens were identified from the sputum in 123 patients. The rate of gram - negative bacteria and gram - positive bacteria were 70.4% and 18.6%, respectively. The most common pathogens of gram - negative bacteria in low respiratory tract were Pseudomonas aeruginosa, among gram - positive bacteria strains the Stphylococus auruginosa was main. Conclusion The gram - negative bacteria were the most pathogens, and they were sensitive to imipenem ; gram - positive bacteria were sensitive to vancomycin. The drug sensitivity test required were significant in proper selection of antibiotics.
出处
《中国急救医学》
CAS
CSCD
北大核心
2008年第4期316-318,共3页
Chinese Journal of Critical Care Medicine
关键词
院内感染
病原学
耐药性
重症监护病房
Nosocomial infection
Pathogen
Drug resistance
Intensive care unit
