摘要
目的研究颅内节细胞胶质瘤（GGs）的临床、影像和病理学特征。方法回顾性分析2001—2005年于复旦大学华山医院神经外科接受手术治疗的27例患者的临床、影像和病理资料及术后随访。结果20例手术全切，7例未完全切除。病理结果示25例为低级别，2例为间变性，胶质和神经元成分共存为其典型特征。平均随访（27．3±18）个月，均未复发。8例术前癫痫发作的患者5例术后完全控制，2例缓解，1例仍有较频繁发作。结论节细胞胶质瘤多属良性，术后患者预后良好。术中应尽可能全切，低级别肿瘤术后可以不进行辅助治疗。
Objective To analyze the clinical, neuroimaging and pathological features of intracranial gangliogliomas （GGs）. Methods A retrospective review was conducted in 27 patients with surgically and pathologically verified GGs. Results Pathological examination showed low grade gangliogliomas （ WHO grade Ⅰ , Ⅱ ） in 25 cases （92.6%） and anaplastic GGs （ WHO grade Ⅲ ） in two （7.4%）. The histopathological hallmark is a combination of glial and neuronal cell elements. The average follow-up period was 27.3 month. There was no evidence of recurrence. In 8 patients with preoperative seizures, the seizures were completly relieved in 5 patients （62. 5% ） after operation and noticeable improvement in two （25%）. Conclusion Intracranial GGs are mostly benign tumors. The prognosis usually is favorable. Surgical purpose should be complete resection and adjuvant therapies should leave for malignant ones.
出处
《中华神经外科杂志》
CSCD
北大核心
2008年第4期249-251,共3页
Chinese Journal of Neurosurgery
