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SELEX技术及其应用研究 被引量:3

SELEX technique and its application
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摘要 配体指数级富集系统进化技术(SELEX)是一种新型的体外筛选技术,其筛选的核酸配基具有靶分子范围广、亲和力和特异性高、稳定性好、制备方便等优点。适配子的功能类似于抗体但明显优于抗体,预测在临床治疗和药物开发等方面具有广泛的应用前景。 Systematic Evolution of Ligands by Exponential Enrichment(SELEX) is known as a new selection technique in vitro, Aptamer selected by it has a large number of target molecules, high affinity and specificity, stability and ease of production regeneration. As aptamer is resembled with antibody but superior to antibody, the aptamer has promising applications prospect in clinical therapy and developing a new drug.
作者 冯香玲 许杨
出处 《食品科技》 CAS 北大核心 2008年第4期175-177,共3页 Food Science and Technology
基金 长江学者和创新团队发展计划项目(IRT0540)
关键词 SELEX 抗体 适配子 SELEX antibody aptamer
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