摘要
目的:促进广东省药品不良反应自发呈报系统数据库的信息标准化建设,对2002年4月28日～2007年7月10日收集的42 255条数据进行规范化整理。方法:结合第15版新编药物学与MCDEX药物临床信息参考(2006).对数据库中的6万多条的药物通用名称进行规范化整理。结合WHO的不良反应术语集和ICD-10疾病系统分类。规整42 255条药品不良反应记录。结果:建立了5 407个药物通用名称规则名,形成4 031个药物通用名称标准名。建立了8 715个不良事件名称规则名。形成2 332个不良事件名称标准名。建立的规则库能自动完成新入库病例的80%的规范化工作。结论:数据标准化将不规范的习惯用语转化成标准化信息,为数据利用如信号检测和数据挖掘提供了基础。
Objective： To promote the information standardization of adverse drug reaction database of spontaneous reporting system in Guangdong, and to normalize the database including 42 255 records collected from 28 April 2002 to 10 July 2007. Method： Over 60 000 genetic drug names were standardized based on New Pharmacology（ 15th edition） and MCDEX Clinical Drug Reference（ 2006 ）. 42 255 records of adverse drug reaction name were normalized with the WHO Adverse Reaction Terminology and International Classification of Diseases-Ten Revision. Result： 5 407 rules of generic drug name and 4 031 standard drug names were created. 8 715 rules of adverse event name and 2 332 standard names of adverse event were established. The rule database was capable of automatic completion 80% of the standardization work of the new cases. Conclusion： The data standardization translated the habit name to standardized information, and provided the foundation for the reuse of data such as signal detection and data mining.
出处
《药物流行病学杂志》
CAS
2008年第2期118-120,128,共4页
Chinese Journal of Pharmacoepidemiology
关键词
自发呈报系统
标准化
药物通用名称
药品不良反应
Spontaneous reporting system
Standardization
Generic drug name
Adverse drug reaction
