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c—myc反义寡核苷酸对大鼠半乳糖性白内障形成的影响 被引量：1

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摘要 白内障是眼科常见病，是主要的致盲性眼病之一。国内外学者正在积极探索治疗白内障的有效方法。随着分子生物学技术的快速发展，白内障的基因治疗已经进入人们的研究范围。癌基因的异常表达与晶状体上皮细胞（1ens epithelial cell，LEC）的增殖分化密切相关，而LEC的增殖分化是白内障发生发展的病理基础。许多研究结果表明，
作者 林宏华 葛正龙 范芳 曾小平
机构地区 安徽省立儿童医院儿内科 遵义医学院生物化学教研室 遵义医学院附属医院眼科
出处 《中华眼科杂志》 CAS CSCD 北大核心 2008年第4期361-364,共4页 Chinese Journal of Ophthalmology
基金 国家自然科学基金（39460077） 贵州省科委基金[（2000）3041]
关键词 白内障形成 反义寡核苷酸 半乳糖性 MYC 分子生物学技术 晶状体上皮细胞 大鼠 基因治疗
分类号 R686 [医药卫生—骨科学]
  • 相关文献

参考文献16

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共引文献28

同被引文献14

  • 1范芳,葛正龙,李长福,曾小平,李海祥.c-myc ASODN对半乳糖诱导的晶状体上皮细胞中cMyc蛋白表达及细胞周期的影响[J].第四军医大学学报,2004,25(11):961-963. 被引量：2
  • 2康可人,黄秀榕,祁明信.榄香烯和姜黄素诱导晶状体上皮细胞凋亡的超微结构改变[J].眼科研究,2006,24(4):382-384. 被引量：5
  • 3林宏华,范芳,陈佳瑜,曾小平,李海祥,葛正龙.半乳糖诱导大鼠晶状体上皮细胞凋亡与白内障形成的关系[J].基础医学与临床,2006,26(8):818-822. 被引量：9
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中华眼科杂志
2008年 第4期

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