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生长抑素受体在胃癌及大肠癌中的表达和临床应用

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摘要 生长抑素(somatostatin,SST)是一种由D细胞分泌的多肽类激素,广泛存在于人体内分泌及外分泌系统中,有广泛的生物学效应,在胃肠道中主要在胃底、胃体、胃窦、大肠和小肠中分泌。近年来,SST抗肿瘤增殖效应及人工合成的生长抑素类似物(somatostatin analogue,SSTA)的临床应用,受到越来越多的关注。SST及SSTA通过细胞表面的生长抑素受体(somatostatin receptor,SSTR)发挥生理效应。
出处 《交通医学》 2008年第2期139-141,共3页 Medical Journal of Communications
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