摘要
目的观察经皮氧分压(PtcO2)在急性呼吸窘迫综合征(ARDS)患者中的变化特点,了解其在ARDS治疗中的作用。方法采用经皮氧分压监测仪对49例ARDS患者实施连续动态监测PtcO2,记录通气前和通气后4、8、16、24 hPtcO2值,同期抽取动脉血检测PaO2、SaO2,记录心率(HR)和平均动脉压(MAP)。并比较存活组与死亡组不同时间PtcO2的差异。结果SaO2、HR、MAP随时间变化的程度不明显(均P>0.05),PtcO2和PaO2随时间变化显著(均P<0.05);存活组(35例)与死亡组(14例)PtcO2比较,差异有显著性意义(P<0.05)。结论PtcO2监测对ARDS治疗能提供连续、可靠的指导作用,PtcO2早期的变化对判断预后有一定帮助。
Objective To explore the characteristic of transcutaneous oxygen （PtcO2） in treatment of acute respiratory distress syndrome （ARDS）. Methods By using transcutaneous oxygen monitor, PtcO2 was dynamically monitored in 49 cases of ARDS before and within 4, 8, 16, 24 h of conventional ventilation （CV） respectively. PaO2 , SaO2 , HR and MAP were also measured at the same time. The difference in PtcO2 was compared between survival group and death group. Results There were no significant differences in values of SaO2 , HR, MAP within 24 h, but there were significant differences in values of PtcO2 and PaO2 before and within 4, 8, 16, 24 h of CV （P〈0. 05 for both）. There was a significant difference in values of PtcO2 between survival group and death group （P〈0.05）. Conclusion Transcutaneous oxygen monitoring could provide continuous and reliable guidance to the treatment of ARDS, and early changes observed from the monitoring could help to predict the prognosis of the disease.
基金
深圳市卫生局2004年度卫生科技计划项目(200405220)
关键词
急性呼吸窘迫综合征
经皮氧分压监测
无创氧监测
预后
acute respiratory distress syndrome
transcutaneous oxygen monitoring
noninvasive oxygen monitoring
prognosis
