摘要
[目的]通过对h-FABP、hs-CRP、cTnT3项指标的联合检测为急性心肌梗死（AMI）的诊断提供可靠依据。[方法]cTnT检测采用金标记免疫渗滤法；hs-CRP检测采用免疫散射比浊法；h-FABP检测采用96T ELISA方法。[结果]健康组与AMI组比较，h-FABP：（5．46±0．19），（23．27±1．77）ng／mL，P〈0．01；cTnT：（0．10±0．01），（0．64±0．11）ng／mL，P〈0．01；hs-CRP：（0．85±0．10），（17．39±4．69）mg／L，P〈0．01；cTnT、hs-CRP、h-FABP在40例AMI患者发作0-3h阳性率分别为50％、55．26％、85％。3项指标联合分析阳性率可达98％。[结论]h-FABP、hs-CRP与cTnT联合检测对AMI早期诊断具有高灵敏性和特异性。
[Objective] To provide the dependable data on diagnosis for AMI through checking the h-FABP, the hs-CRP and the cTnT jointly. [ Methods] The cTnT was detected by the immunogold filtration assay. The hs-CRP was by the immune nephelometer measure. The h-FABP was by the 96 tests ELISA. [Results] Copared control group with AMI group, h-FABP：（5.46±0.19） ,（23.27±1.77）ng/mL,P 〈0.01,cTnT： （0.10 ±0.01） ,（0.64±0.11）ng/mL,P 〈0.01,hs-CRP ： （0.85±0.10）, （17.39±4.69） mg/L, P 〈 0.01, during 3 hours the positive rate of cTnT, hs -CRP, h-FABP was 50% , 55.26% , 85% respectively in 40 patients of AMI. The positive rate of checking jointly creased to 98%. [Conclusion] The checking jointly of the h-FABP, the hs-CRP and the cTnT is sensitive and differential for the early diagnosis for AMI.
出处
《大连医科大学学报》
CAS
2008年第2期170-172,共3页
Journal of Dalian Medical University
