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四种代谢综合征诊断标准在初发2型糖尿病人群中应用的比较 被引量:7

Evaluation of the application of four diagnostic criteria of metabolic syndrome in patients with newly-diagnosed type 2 diabetes mellitus
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摘要 目的比较WHO(1999年)、国际糖尿病联盟(IDF,2005年)、美国国家胆固醇教育计划成人治疗组(NCEP-ATPⅢ,2001年)的代谢综合征(MS)诊断标准和中华医学会糖尿病学分会(CDS,2004年)制定的MS诊断标准在我国初发老年2型糖尿病人群中应用的异同。方法对初诊2型糖尿病患者1399例进行MS诊断相关指标测定,按年龄分为老年组259例和非老年组1140例,计算不同标准的MS诊断率,比较两组结果的异同。结果(1)MS患病率以WHO诊断标准检出率最高(68.0%),NCEP-ATPⅢ标准次之(54.8%),CDS标准(47.9%)与IDF标准(46.7%)相近,NCEP-ATPⅢ标准、WHO诊断标准、IDF标准与CDS标准诊断率比较,差异均有统计学意义(P〈0.01);(2)NCEP-ATPⅢ标准与CDS标准诊断符合率较高,WHO、IDF标准稍差。结论对初诊2型糖尿病患者,应用WHO标准诊断MS阳性率最高,NCEP标准与CDS标准一致性最高,WHO诊断标准可能更适合本组初发老年2型糖尿病患者。 Objective To compare the prevalences of metabolic syndrome(MS) diagnosed with 4 diagnostic criteria by the World Health Organization (WHO, 1999), the Inrernational Diabetes Federation(IDF, 2005), the Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults(NCEP ATPⅢ, 2001) and the Chinese Medical Association Diabetes Branch(CDS) respectively. Methods The interrelated parameters were measured in 1399 patients with newly-diagnosed type 2 diabetes mellitus. All the patients were divided into 2 groups: elderly group(259 cases) and non-elderly group(1140 cases),and the different prevalences diagnosed by 4 diagnostic criteria in 2 groups were compared. Results The MS prevalence was 68. 0%, 47.9%, 46.7% and 54.8% in elderly group by WHO, CDS, IDF and NCEP ATPⅢ respectively. The consistent rate was 76. 1% between WHO and CDS, and 70. 3% between IDF and CDS, and 81.9% between NCEP ATPⅢ and CDS. Conclusions The WHO definition may be more suitable for MS diagnosis in elderly patients with newly-diagnosed type 2 diabetes mellitus.
出处 《中华老年医学杂志》 CAS CSCD 北大核心 2008年第4期252-255,共4页 Chinese Journal of Geriatrics
基金 国家“十五”科技攻关项目(2001BA702B01)
关键词 2型糖尿病 代谢综合征 患病率 胆固醇 Diabetes mellitus, type 2 Metabolic syndrome X
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