摘要
DNA甲基化及其调节酶是近年来表观遗传学研究的热点。DNA甲基化异常可影响某些基因的表达,导致自身免疫性疾病的发生发展。深入研究DNA甲基化在自身免疫性疾病中的作用,有利于阐明自身免疫性疾病的发病机制,为治疗这些疾病提供新的线索。
Recent studies on DNA methylation and its regulatory enzymes, seem hot to researches of epigenetics. Abnormal DNA methylation can influence the expression of certain genes, inducing occurrence and development in autoimmune diseases. These deeper epigenefic studies of the role of DNA methylation in the induction of autoimmune diseases, may give us clues towards elucidation of the pathogenesis of autoimmune diseases and development of new therapeutic strategies for these diseases.
出处
《国际病理科学与临床杂志》
CAS
2008年第2期161-164,共4页
Journal of International Pathology and Clinical Medicine
