摘要
目的 评估固尔苏预防早产儿呼吸窘迫综合症（NRDS）的临床疗效及安全性。方法将60例早产儿分为两组，观察组生后气管内滴入固尔苏，对照组不用固尔苏，两组患儿均给予相同的综合治疗，比较两组死亡或放弃治疗的比例、发生NRDS的比例、需要呼吸机治疗的例数、发生并发症的比例及胸片改变的严重程度。结果 观察组死亡或放弃治疗的比例较对照组下降。观察组发生NRDS的比例、需要呼吸机治疗的例数、发生并发症的比例均较对照组少。两组发生NRDs的患儿胸片改变观察组较对照组程度轻。结论 早产儿生后预防性应用固尔苏可以降低观察组NRDs发生率及减轻发病程度，降低死亡率及减少并发症，固尔苏使用是安全的。
Objective To study the efficacy and safety of Curosurf in prevention of respiratory distress syndrome （NRDS） of premature infants. Methods Sixty premature infants were divided into observable group and control group. Thirty neonates of observable group received Curosurf via endotracheal tube after birth, and thirty infants of cbntrol group didn＇t get Curosurf .All of the other supportive treatment were same in both groups. The incidents of death ,cases needed mechanical ventilation, complication and the severity of X-ray were compared between the two groups. Results The incidents of death or giving up treatment in observable group were significantly lower than control group. The incidents of NRDS, cases needed mechanical ventilation and complication in observable group were fewer than control group. The severity of NRDS on chest X-ray in observable group was milder than that in control group. Conclusion The prophylactic treatment with Curosurf for premature infants can reduce the incidence of NRDS in observable group and decrease its severity, and lower the rate of death and reduce complication. It is safe to use Curosurf for premature infants.
出处
《国际医药卫生导报》
2008年第7期43-45,共3页
International Medicine and Health Guidance News
关键词
固尔苏
呼吸窘迫综合症
早产
Curosurf Respiratory disease syndrome Premature
