摘要
目的探讨老年性带状疱疹患者治疗前后细胞免疫功能变化及临床意义。方法对65例老年性带状疱疹患者分别在治疗前、治疗后采用流式细胞仪检测T淋巴细胞亚群（CD3、CD4及CD8）、自然杀伤（NK）细胞。结果老年性带状疱疹患者治疗前的外周血CD4、CD4／CD8低于健康对照组（P〈0.05），而CD3、CD8及NK细胞高于健康对照（P〈0．05）；治疗后CD4、CD4／CD8升高，而CD3和CD8降低，均与治疗前有显著差异（P〈0．05），但与健康对照组比较仍有差异（P〈0．05）。结论老年性带状疱疹患者存在不同程度的细胞免疫功能低下，其功能状况直接影响病情和疗效。
Objective To study the change of cell immune function after treatment in old patients with herpes zoster. Methods The and its clinic significance T-lymphocyte subpopulation （ CD3, CD4 and CD8） and NK cells were evaluated by flow cytometry in 65 cases of old patients with herpes zoster before and after treatment. Results Before treatment, it＇s showed the CD4, CD4/CD8 were significantly lower, while the CD3, CD8 and NK cells were significantly higher than normal subjects （P〈0.05）.After treatment, CD4, CD4/CD8 were significantly increased, CD3, CD8 were significantly decreased, which were all much better than before（P〈0.05）,while there were still marked discrepancy compared with normal subjects （p〈0.05）.Conclusions These results revealed that cellular immunity is impaired in old patients with Herpes zoster, which was correlated with the serious of illness and the curative effect.
出处
《国际医药卫生导报》
2008年第9期36-37,共2页
International Medicine and Health Guidance News
