摘要
目的为探讨甘草锌颗粒治疗寻常性痤疮的临床疗效及安全性。方法采用随机对照的临床实验。对照组（A组）口服克林霉素分散片，同时外涂达芙文；治疗组（B组）除在对照组治疗的基础上，同时服用甘草锌颗粒5克（1包），每日3次，共4周，1个月后改5克（1包），每日1次，4周后停药。治疗4周、8周末评价疗效及不良反应。结果治疗组治愈50例，显效21例，有效率为74．56％；对照组治愈31例，显效16例，有效率为51．65％，两组差异有统计学意义（x^2值分别为8．45、7．98，均P〈0．05）。结论甘草锌颗粒辅助治疗痤疮效果确切，值得临床推广。
Objective To investigate the effects and safety of therapy acne vulgarize with Licorzine Granules. Methods A randomized controlled clinical study was performed in 184 patients with acne vulgaris. The patients were divided into two groups. The first group was treated with oral clindamycin and topical Differin（Adapalene）.The second group was treated Licorzine Granules and also with the first group. The efficiency and side effect were evaluated at the end of every four weeks. Results there was statistical difference between the first group and the second group. Conclusion Combination of Licorzine Granules oral clindamycin and topical Differin showed a good clinical efficacy and no severe side effect in the treatment of acne vulgarize.
出处
《国际医药卫生导报》
2008年第9期59-60,共2页
International Medicine and Health Guidance News
