摘要
目的 探讨血清胱抑素C和血清骨钙素浓度检测对糖尿病患者早期肾功能损害诊断的临床价值。方法 研究组测定95例Ⅱ型糖尿病早期。肾脏损害患者的血清胱抑素C和血清骨钙素的浓度，对照组测定85例Ⅱ型糖尿病早期。肾脏损害患者的血清肌酐和血清尿素氮的浓度，比较两种方法异常率。结果 联合检测血清胱抑素C和血清骨钙素的浓度，异常率是31．5％，联合检测血清肌酐和血清尿素氮的浓度，阳性率是16.5％。两组比较有显著差异，P〈0．05．结论 测定血清胱抑素C浓度和血清骨钙素的浓度，可作为早期糖尿病。肾病损害的诊断指标，而且敏感性和特异性比血清肌酐和尿素氮更高，值得临床推广应用。
Objective To discuss the clinical value of together with Serous Cystatin C （Cys C） and Osteocalcin （OST） in early Diabetic nephropathy. Methods The study group was to detect Serous Cystatin C and Osteocalcin together in 95 patients of early diabetic nephropathy ,and the controlled group was to detect creatinine（CR） and blood urea nitrogen （BUN） in 85 cases ,then compare the rate of abnormal cases. Result The abnormal rate in study group was 31.5% and the controlled group was 16.5%.Conclusion It is a good index to detect Serous Cystatin C and Osteocalcin together in patients of early diabetic nephropatby, It is more sensitive and accurate than creatinine（CR） and blood urea nitrogen （BUN）.It is worth of clinical spreading and application
出处
《国际医药卫生导报》
2008年第10期12-14,共3页
International Medicine and Health Guidance News
关键词
糖尿病
肾病胱抑素C
骨钙素肌酐
尿素氮
Diabetic nephropathy Cystatin C Osteocalcin Creatinine Blood urea nitrogen
