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衣原体感染不孕不育患者血清中自身抗体的检测 被引量:9

Chlamydia Infection of Infertile Patients with Detection of Autoantibody in Serum
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摘要 目的:探讨衣原体感染与血清中抗精子抗体(AsAb)、抗心磷脂抗体(AcA)、抗子宫内膜抗体(EMAb)之间的关系。方法:用ELISA法检测120例衣原体感染不育男性(男性衣原体感染组)和55例正常生育男性(男性正常对照组)的血清中AsAb、ACA;检测142例衣原体感染不孕女性(女性衣原体感染组)和60例正常生育女性(女性正常对照组)的血清中AsAb、ACA、EMAb。结果:男、女衣原体感染组AsAb、ACA检出率高于相应对照组,具有显著性差异(P值均<0.05);女性衣原体感染组EMAb检出率高于女性对照组,具有显著性差异(P<0.05)。结论:生殖道衣原体感染和与不孕不育有着密切的相关性,且AsAb、ACA、EmAb的产生与衣原体感染有关。 Objective: To study the relationship ofchlamydia infection and AsAb, ACA, and EMAb in serum. Methods: AsAb and ACA in serum of 120 infertile men infected by chlamydia ( male chlamydia infection group) and 55 fertile men (male normal group) were measured using ELISA. AsAb,ACA and EmAb in serum of 142 infertile women infected by chlamydia (famale chlamydia infection group) and 60 fertile women (famale normal group) were measured. Results: The positive rate of AsAb and ACA in serum ofchlamydia infection groups were higher than normal groups, and there were significant difference between the infected groups and fertile groups (P〈0.05).The positive rate of EMAb in serum of female chlamydia infection group were higher than female normal group,and there was significant difference between the two groups (P〈0.05). Conclusion: There is intimate correlation between chlamydia infection and infertility, moreover AsAb,AcA and EmAb relate to chlamydia infection.
出处 《现代生物医学进展》 CAS 2008年第6期1096-1097,共2页 Progress in Modern Biomedicine
关键词 不孕不育症 衣原体 抗精子抗体 抗心磷脂抗体 抗子宫内膜抗体 infertility Chlamydia AsAb ACA EmAb
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