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结直肠肿瘤标志物CDX2的研究现状 被引量:9

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摘要 作为一种新发现的特异性的核转录因子,尾型同源盒基因(CDX2)在成人正常情况下严格表达于肠道上皮,其与肠黏膜的发生、发展及维持有关。它对正常和肿瘤性的肠上皮均有相对特异性和敏感性,用它做免疫组织化学染色可以用来鉴别转移性肿瘤是否来源于肠道。笔者仅就CDX2的结构、分布、功能及其致瘤机制和分子生物学特征的研究现状作一综述。
作者 胡泽成 赵华
出处 《中国普通外科杂志》 CAS CSCD 2008年第4期391-393,共3页 China Journal of General Surgery
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参考文献28

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二级参考文献8

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