摘要
目的探讨经导管冷冻消融治疗心房颤动(简称房颤)的安全性和有效性。方法2005年1月至2007年3月本中心共有24例房颤患者接受了经导管冷冻消融肺静脉隔离术,其中22例为阵发性房颤,2例为持续性房颤,消融的终点是肺静脉电位消失。随访成功的定义为术后3个月后无症状性快速性房性心律失常发生。结果22例实现肺静脉电位消失(91.7%),随访15.9±7.5个月,其中18例恢复窦性心律未再发作房颤(8例未服抗心律失常药物),消融首次成功率81.8%(18/22),2例出现心房扑动,1例出现短阵房性心动过速。严重并发症包括1例术后心包压塞,1例一过性窦性停搏伴下壁导联ST段抬高,1例一过性脑气栓,无死亡病例。其中心包压塞者进行了心包穿刺引流术后痊愈。ST段抬高性心室停搏予心室起搏、硝酸甘油静脉点滴后好转。一过性脑气栓的患者经过对症治疗后好转,未留下神经系统后遗症。结论经导管冷冻消融治疗房颤是较安全和有效的。
Objective To evaluate the long-time effects of catheter cryoablation for the treatment of atrial fibrillation （AF）. Methods Between Janurary 2005 and March 2007, there were 24 patients with AF accepted transvenous catheter cryoablation treatment, most of them presented paroxysmal AF, only two were persistent AF. The ablation end-point was defined as pulmonary vein （PV） isolation. Results 22 patients （91.7%） were performed this end-point. Severe complication included 1 cases of pericardial tamponade, 1 case of cardiac arrest with ST elevation and 1 case of temporary cere- bral gas embolism. All these patient were recovered, and there was no death case. During a mean follow-up period of 15. 9±7.5 month, 18 patients （81.8%） were in sinus rhythm with （10） or without antiarrhythmic drugs （8）. 2 patients suffered from atrial flutter, 1 patient had paroxysmal atrial tachycardia. Conclusion Transvenous catheter cryoablation is an effective and safe therapy for patients with AF.
出处
《中国心脏起搏与心电生理杂志》
2008年第2期119-121,共3页
Chinese Journal of Cardiac Pacing and Electrophysiology
