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核因子-κB与类风湿关节炎关系研究进展

Research progress of the correlation between nuclear factor-κB and rheumatoid arthritis
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摘要 概述了核因子-κB的生物学特性、核因子-κB的活化与在类风湿关节炎发病中的关系,以及目前临床治疗类风湿关节炎的药物,包括非甾体类抗炎药、糖皮质激素、慢作用抗风湿药、中药等调控核因子-κB活性的研究现状,为深入探讨类风湿关节炎的发病机制,研发新的抗类风湿关节炎药物提供研究依据。 This paper briefly introduces the biologic property of nuclear factor -κB ( NF -κB), relationship between NF -κB activation and rheumatoid arthritis (RA) onset, and regulation of NF -κB activation by anti - rheumatism drugs including nonsteroidal anti -inflammatory drugs, glucocorticoid, slow -acting anti -rheumatism drug and traditional Chinese medicine, and then provides the basis for exploitation of new anti - rheumatism drugs.
作者 陈刚
出处 《重庆工商大学学报(自然科学版)》 2008年第3期294-297,共4页 Journal of Chongqing Technology and Business University:Natural Science Edition
基金 重庆市教委资助项目(KJ060702)
关键词 类风湿关节炎 核因子-ΚB 药物 rheumatoid arthritis nuclear factor -κB drug
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参考文献23

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