摘要
比较了重离子３０ＭｅＶ／ｕ４０Ａｒ１５＋和６０Ｃｏγ射线对体外培养的人肝癌细胞株ＳＭＭＣ７７２１的辐射效应，用活体和固定的方法观察了辐射处理后细胞死亡的过程。结果表明：无论是重离子还是γ射线，都能对细胞造成严重损伤，影响细胞存活百分数；同时，重离子比γ射线对细胞有更显著的杀伤效果，在处理后第４８ｈ，细胞存活率为５０％时，重离子的ＲＢＥ约为１５。
Radiation effects of cultured human hepatoma cell line SMMC7721 irradiated by heavy ion 30MeV/u 40Ar15+ and 60Co γray are compared in this study Process of the cell death after irradiation is studied by observing the alive cells and the fixed cells The results show that both heavy ion and γray can cause serious damage to the cells, and affect the cell survival fraction Meanwhile, the killing effect on cells by heavy ion is stronger than that by γray At the 48th hour after treatment, the relative biological effectiveness of heavy ion is 15 based on cell survival of 50%
出处
《辐射研究与辐射工艺学报》
CAS
CSCD
北大核心
1997年第4期249-252,共4页
Journal of Radiation Research and Radiation Processing
基金
国家科委"九五"攀登计划(B)资助项目
关键词
重离子
Γ射线
人肝癌细胞
相对生物学效应
Heavy ion
γray
Human hepatoma cell line
Survival fraction
Relative biological effectiveness
