期刊文献+

绒癌脑转移的神经外科治疗 被引量:6

Neurosurgery for Brain Metastases of Choriocarcinomas
下载PDF
导出
摘要 目的探讨绒癌脑转移神经外科诊断、治疗原则及手术方法。方法回顾性分析1995年1月至2007年1月间在我院确诊为绒癌脑转移而行神经外科手术治疗的21例患者的临床资料,其中19例术后接受了联合方案化疗。结果21例绒癌脑转移患者中,术后症状完全缓解11例,部分缓解8例,死亡2例。其中14例随访1~10年,存活11例,死亡3例;失访5例。结论对于绒癌脑转移患者,早期诊断与及时有效的化疗是改善预后的关键,积极的神经外科手术是挽救患者生命,获得进一步化疗机会的重要方法。 Objective To study the diagnosis and treatment of brain metastasis of choriocarcinomas. Methods The clinical data of 21 patients with brain metastases of choriocarcinmas, who underwent surgery and were treated by chemotherapy in our hospital from January, 1994 to January, 2007, were analyzed retrospectively. Results Of 21 patients with brain metastases of choriocarcinomas, 11 achieved complete remission, 8 partial remission, and 2 died. Of 14 followed up from 1 to 10 years, 11 survived and 3 died. Conclusions The prognoses are bad in the patients with intracranial metastases of choriocarcinomas. Early diagnosis and chemotherapy play the key role in the management of the patients with brain metastases of choriocarcinoma and neurosurgery also is the important method to treat them.
出处 《中国临床神经外科杂志》 2008年第5期266-268,共3页 Chinese Journal of Clinical Neurosurgery
关键词 绒癌 脑转移 神经外科手术 化疗 Choriocarcinoma Brain metastasis Neurosurgery Chemotherapy
  • 相关文献

参考文献8

  • 1Song HZ, WU BZ. Brain metastasis in choriocarcinoma and malignant mole: an analysis of 98 cases [J]. Chin Med J, 1979, 92(3): 164-174.
  • 2Yordan EL Jr, Schlaerth J, Gaddis O, et al. Radiation therapy in the mangement of gestational chriocarcinoma metastatic to the central nervous syste[J]. Obstet Gynecol, 1987, 69(4): 627-630.
  • 3石一复,金杭美.绒癌脑转移23例分析[J].实用妇科与产科杂志,1993,9(3):153-155. 被引量:3
  • 4向阳,杨秀玉,宋鸿钊,李志英,崔竹梅,万希润.恶性滋养细胞肿瘤脑转移的疗效分析[J].中华妇产科杂志,2001,36(7):417-420. 被引量:16
  • 5Baertschi E, Notter M, Mironov A, et al. Cerebral metastasis in choriocarcinoma a case report [J]. Schweiz Rundsch Med Prax, 2003, 92(16): 763-768.
  • 6Korinth MC, Delonge C, Hutter BO, et al . Prognostic factors for patients with microsurgically resected brain metas tases [J]. Onkologie, 2002, 25(5): 420-425.
  • 7王业忠,刘祺,彭心宇.脑转移瘤的治疗[J].中国临床神经外科杂志,2005,10(1):74-76. 被引量:5
  • 8Bindal RK, Sawaya R, Leavens ME, et al . Surgical treatment of multiple brain metastases [J]. J Neurosurg, 1993, 79(2): 210-216.

二级参考文献22

  • 1王业忠,吴永刚,文世宏,赵博熙,朱兆川,李锋,李新霞,刘春霞.54例脑转移瘤的临床分析及免疫组化研究[J].农垦医学,2001,23(2):73-74. 被引量:3
  • 2SchleusenerJT, Tazelaar HD, Jung SH, et al . Neuroendocrine differentiation is an independent prognostic factor in chemotheraphy-treated nonsmall cell lung carcinoma [J].Cancer, 1996, 77(7): 1284-1291.
  • 3Kim YS, Kondziolka, Flickinger JC, et al. Stereotactic radiosurgery for patients with nonsmall cell lung carcinoma metastatic to the brain [J]. Cancer, 1997, 80(11): 2075-2083.
  • 4Farnell GF, Bucker JC, Cascino TL, et al. Brain metastases from colorectal carcinoma [J]. Cancer, 1996, 78(4): 711-716.
  • 5Arbit E, Wronski M, burt M, et al. The Treatment of patients with recurrent brain metastases [J]. Cancer, 1995, 76(5): 765-773.
  • 6Nguyen LN, Maor MH, Oswald M J, et al . Brain metastases as the only manifestation of an undetected primary tumor[J]. Cancer, 1998, 83(10): 2181-2184.
  • 7Bindal AK, Bindal RK, Hess KR, et al. Surgery versus radiosurgery in the treatment of brain metastasis [J]. Neurosurgery, 1996, 84(5): 748-754.
  • 8Boogerd W, Dalesio O, Bais E, et al . Response of Brain Metastases From Breast Cancer to systemic chemotheraphy[J]. Cancer, 1992, 69((4): 972-980.
  • 9Bakri Y,J Reprod Med,1994年,39卷,179页
  • 10Jones W B,Gynecol Oncol,1990年,38卷,234页

共引文献20

同被引文献31

  • 1杨隽钧,向阳,杨秀玉,万希润,王任直,任祖渊,殷红梅,郭卫东,区小牧.绒毛膜癌脑转移急诊行开颅手术的临床分析[J].中华妇产科杂志,2005,40(5):335-338. 被引量:4
  • 2葛培林,陈治标,晏炳元,叶应湖,陈坚,王国安.貌似脑血管意外的瘤卒中临床分析[J].卒中与神经疾病,2005,12(4):238-239. 被引量:2
  • 3Suresh TN, Santosh V, Shastry Kolluri VR, et al. Intracranial haem- orrhage resulting from unsuspected choriocarcinoma metastasis. Neurol India,2006,49 (3) :231-236.
  • 4李玉红,陈少波,郭晓萍.EMA-CO方案治疗1例绒癌肺转移的护理[J].现代护理,2010,7(2):94-95.
  • 5Johnson RH, Chien FL, Bleyer A. Incidence of breast cancer with distant involvement among women in the United States, 1976 to 2009 [ J ]. JAMA,2013,309:800.
  • 6Tabouret E, Bauchet L, Carpentier AF. Brain metastases epidemio- logy And biology[J]. Bull Cancer,2013,100:57.
  • 7Muenkovi V,Lazovi B, Mirkovi L,et al. Brain metastases of ehorio- carcinoma a report on two cases[J]. Vojnosanit Pregl ,2013 ,70 :968.
  • 8Gollego J, Hildebrand J [ J ]. Brain metastases. Handb Clin Neurol. 2014;121:1143.
  • 9Kyritsis AP, Markoula S, Levin VA. A systematic approach to the management of patients with brain metastases of known or unknown primary site [ J ]. Cancer Chemother Pharmacol,2012,69 : 1.
  • 10Polyzoidis KS, Miliaras G, Pavlidis N. Brain metastasis of unknown primary:a diagnostic and therapeutic dilemma [ J ]. Cancer Treat Rev. 2005,31:247.

引证文献6

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部