摘要
鱼类抗病毒非特异性免疫系统主要包括自然杀伤细胞、单核巨噬细胞系统及干扰素,蛋白因子白介素、趋化因子、肿瘤坏死因子及干扰素诱导产生的蛋白激酶PKR、Mx蛋白、主要组织相容性蛋白、一氧化氮合成酶在鱼类抗病毒免疫中发挥重要的作用。了解病毒与鱼体之间的相互作用机理,为鱼类病毒性疾病防控奠定基础。
The fish anti-viral nonspecific immunity system includes natural killer cells, mononuclear phagocyte system and interferon. Some protein factors including interleukin, chemokine, tumor necrosis factor, protein kinase, Mx protein, major histocompatibility complex and nitric oxide synthase play an important role in anti-viral immune mechanism in fish. Further understanding of the antiviral mechanism lay the foundation for prevention and treatment of viral diseases in fish.
出处
《动物医学进展》
CSCD
2008年第5期99-103,共5页
Progress In Veterinary Medicine
基金
国家自然科学基金项目(30471338)
关键词
鱼类
抗病毒
非特异性免疫
fish
anti-viral
nonspecific immuneity
