摘要
目的探讨异丙酚复合氟比洛芬酯、芬太尼、力月西,在门诊无痛胃镜检查中的效果。方法90例患者随机分为3组:A组先静脉注射氟比洛芬酯1.0 mg/kg,3 min后再静脉注射异丙酚;B组先静脉注射芬太尼1.0μg/kg,再静脉注射异丙酚;C组先静脉注射力月西0.02 mg/kg,再静脉注射异丙酚。监测并记录MAP、HR、SpO2、异丙酚的总用量、病人清醒时间、SpO2下降低于90%的次数以及头昏、嗜睡等不良反应。结果B组术中MAP、HR、SpO2较术前明显下降;B、C两组的清醒时间长于A组、头昏嗜睡等不良反应明显的发生多于A组。结论3组方法均可完成无痛胃镜检查,但以异丙酚伍用氟比洛芬酯组更为安全、有效。
Objective To compare the effect of propofol complex with flurbiprofen axetil,fentanyl,midazolam on outpatient painless gastroscopy. Methods 90 patients scheduled for gastroscopy were randomly divided into group A, B and C. The patients of group A were given flurbiprofen axetil 1.0 mg/kg intravenously three minutes before propofol was injected intravenously. The patients of group B were given fentanyl 1.0μg/kg intravenously and the patients of group C were given midazolam 0.02 mg/kg intravenously three minutes before propofol was injected intravenously. The gastroscope was inserted when patient showed unconsciousness and no reaction to dietation.MAP、 HR、SpO2、total dosage of propofol 、 the time patients taking to be awake、 frequency of SpO2 descending more than 10% .,adverse effects of dizziness and lethargy were monitored and recorded.Results MAP、HR、SpO2 in group B descended during the surgery compared with those before the surgery（ P 〈0.05）.The time patients taking to be awake in group B、C was longer than that in A group. Adverse effects of dizziness and lethargy in group B, C happened more frequently than those happened in group A. Conclusion All these drugs can be used in painless gastrescopy, but propofol complex with flurbiprofen axeti is more effective and safe.
出处
《黑龙江医学》
2008年第5期369-370,共2页
Heilongjiang Medical Journal
