摘要
目的探讨糖化血清蛋白(GSP)及1,5-脱水葡萄糖醇(1,5-AG)在妊娠期糖代谢异常诊断中的价值。方法对正常妊娠组、糖筛查异常组及糖耐量异常组进行空腹葡萄糖、口服葡萄糖50g筛选、GSP、1,5-AG测定。结果糖筛查异常组GSP水平为(154±18)μmol/L、糖耐量异常组GSP水平为(157±26)μmol/L,与正常妊娠组[(136±30)μmol/L]比较,差异有统计学意义(P<0.01)。糖筛查异常组和糖耐量异常组1,5-AG水平分别为(57.3±30.2)μmol/L、(45.2±25.7)μmol/L,显著低于正常妊娠组水平[(84.5±35.6)μmol/L,P<0.01]。结论GSP、1,5-AG可作为妊娠期糖代谢异常筛查及诊断指标。
Objective To investigate the diagnostic value of glucosylated serum protein（GSP） and 1,5-Anhydro-D- glucitol （1,5-AG） in abnormal glucometabolism in pregnancy. Methods The fasting blood glucose （FBG）, 50 g glucose challenge test（ GCT）, GSP, 1,5-AG in normal pergnancy group, abnormal GCT pergnancy group and abnormal o- ral glucose tolerance test（OGTT） pregnancy group were determined. Results The levels of GSP in abnormal GCT preg-nancy group and abnormal OGTT group were （154±18） μmol/L, （157±26） μmol/L respectively, and they were significantly higher than that in normal pregnancy group （[136±30]μmol/L,P 〈 0.01 ）. The levels of 1,5-AG abnormal GCT pregnancy group and abnormal OGTT group were （57.3±30.2）μmol/L and （45.2±25.7）μmol/L respectively, and they were significantly lower than that in normal pregnancy group （[84.5±35.6 ] μmol/L, P〈0.01 ）. Conclusions GSP and 1,5-AG are indicators for screening and diagnosing pregnant glucometabolism abnormality.
出处
《检验医学》
CAS
北大核心
2008年第3期268-270,共3页
Laboratory Medicine
关键词
1
5-脱水葡萄糖醇
糖化血清蛋白
糖筛查异常
妊娠
糖耐量异常
1,5-Anhydro-D-glucitol
Glucosylated serum protein
Abnormal glucose challenge test
Pregnancy
Oral glucose tolerance test
